5731-11-3 Usage
Description
4'-BROMO-4-BIPHENYL CARBOXYLIC ACID, also known as 4''-Bromo[1,1''-biphenyl]-4-carboxylic Acid, is an organic compound with a unique chemical structure that features a biphenyl core and a carboxylic acid functional group. It is characterized by the presence of a bromine atom at the 4' position, which imparts specific properties to the molecule.
Uses
Used in Pharmaceutical Industry:
4'-BROMO-4-BIPHENYL CARBOXYLIC ACID is used as a novel A-C ring steroidomimetic inhibitor for targeting 5α-reductase (5αR) type 1 and 2. It serves as a potential therapeutic agent in the treatment of various conditions related to the overactivity of 5α-reductase enzymes, such as benign prostatic hyperplasia (BPH) and androgenetic alopecia.
4'-BROMO-4-BIPHENYL CARBOXYLIC ACID's ability to inhibit 5α-reductase enzymes makes it a valuable candidate for drug development, as it can help regulate the conversion of testosterone to dihydrotestosterone (DHT), which is involved in the progression of these conditions. By modulating the activity of 5α-reductase, 4'-BROMO-4-BIPHENYL CARBOXYLIC ACID may offer a new approach to managing hormone-related disorders and improving patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 5731-11-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,3 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5731-11:
(6*5)+(5*7)+(4*3)+(3*1)+(2*1)+(1*1)=83
83 % 10 = 3
So 5731-11-3 is a valid CAS Registry Number.
5731-11-3Relevant articles and documents
Azabenzimidazole tetrahydrofuran derivatives
-
Page/Page column 74, (2018/02/28)
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
Synthesis of aromatic carboxylic acids by carbonylation of aryl halides in the presence of epoxide-modified cobalt carbonyls as catalysts
Boyarskii,Zhesko,Lanina
, p. 1844 - 1848 (2007/10/03)
A new procedure was developed for synthesis of aromatic and heteroaromatic acids and their derivatives (esters, salts) by carbonylation of the corresponding aryl halides. The acids are selectively formed in a high yield under very mild conditions. Highly active catalytic systems, base-containing alcoholic solutions of cobalt carbonyl modified with epoxides, were used to activate aryl halides. 2005 Pleiades Publishing, Inc.
