5733-03-9

Basic information

• Product Name: 1H-Cyclopenta[c]furan-1-one, hexahydro-
• CAS NO: 5733-03-9
• Molecular Formula: C7H10O2
• Molecular Weight: 126.155
• Mol File: 5733-03-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Cyclopenta[c]furan-1-one, hexahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Cyclopenta[c]furan-1-one, hexahydro-(5733-03-9)
• EPA Substance Registry System: 1H-Cyclopenta[c]furan-1-one, hexahydro-(5733-03-9)

Safety Data

• Hazardous Substances Data: 5733-03-9(Hazardous Substances Data)

Usage

Physical state

Colorless liquid It is a liquid that is colorless in appearance.

Odor

Sweet, nutty It has a pleasant aroma that is described as sweet and nutty.

Uses

Flavorings and fragrances, solvent, precursor in organic synthesis This compound is commonly used in the production of flavorings and fragrances, as a solvent, and as a starting material in the synthesis of other organic compounds.

Toxicity

Low toxicity, generally regarded as safe for use in food and cosmetics It is considered to be safe for use in food and cosmetic products, but it should be handled with care.

Safety precautions

Flammable, may cause skin and eye irritation It is important to handle this compound with care due to its flammable nature and potential to cause skin and eye irritation.

Upstream product

• 113335-71-0 2-Iodo-hept-6-enoic acid tert-butyl ester 
• 113335-69-6 2-Iodo-hept-6-enoic acid methyl ester 

Downstream Products

• 1233387-89-7 (3aR,6aS)-3a-(3,4-dichlorophenyl)-2-methyloctahydrocyclopenta[c]pyrrole 
• 1233387-85-3 (3aS,6aR)-3a-(3,4-dichlorophenyl)-2-methyloctahydrocyclopenta[c]pyrrole 
• 1233387-79-5 cis-3a-(3,4-dichlorophenyl)octahydrocyclopenta[c]pyrrole 

Relevant articles and documents

Atom Transfer Cyclization Reactions of α-Iodo Esters, Ketones, and Malonates: Examples of Selective 5-Exo, 6-Endo, 6-Exo, and 7-Endo Ring Closures

The preparation and free-radical cyclization reactions of unsaturated α-iodo esters, ketones, and malonates have been investigated.For example, sunlamp irradiation of methyl 2-iodo-6-heptenoate in benzene in the presence of 10 mol percent hexabutylditin produces methyl 2-(iodomethyl)cyclopentanecarboxylate (cis and trans) and methyl 3-iodocyclohexanecarboxylate in a ratio of 93/7 in a combined yield of 86percent.The γ-iodo carbonyl products can either be isolated (in most cases) or converted in situ to deiodinated products (with Bu3SnH) or lactones (by heating).Five-, six-, or seven-membered rings selectively form, depending on chain length and alkene substitution.Terminal alkene substituents favor exo cyclization while internal alkene substituents promote endo cyclization.A preference for endo closure is also observed when there is a carbonyl group "inside" the forming ring.A detailed analysis of reaction rates indicates that these isomerizations proceed by an iodine atom transfer chain mechanism, and thus the observed selectivities are due to the kinetic substituent effects.The results contrast the thermodynamically controlled hydrogen atom transfer cyclizations of Julia.A new procedure for the removal of tin byproducts is described.