57346-02-8Relevant articles and documents
Reaction of Methoxyoxirane with Inorganic Phosphate and Reflections on SN2-Reactivity
Pitsch, S.,Eschenmoser, A.
, p. 2383 - 2396 (2007/10/02)
In the context of the chemistry of potentially prebiological natural products it would be imported to know whether, from a chemical point of view, glycoaldehyde phosphate could be considered as a potentially prebiological natural material.In this connection, the reaction of rac. methoxyoxirane with inorganic phosphate in aqueous solution was checked: it does not produce glycoaldehyde phosphate but the 1-phosphate of 1-methoxy-1,2-ethanediol instead.In this context, earlier reflections on the question of how electronegative substituents influence SN2-reactivity are recorded. methoxyoxirane, glycolaldehyde phosphate, SN2-reactivity, nitrogen-inversion
