57362-77-3

Basic information

• Product Name: 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER
• Synonyms: 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER;Ethyl 4-iodo-3-nitrobenzoate
• CAS NO: 57362-77-3
• Molecular Formula: C₉H₈INO₄
• Molecular Weight: 321.06859
• Mol File: 57362-77-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER(57362-77-3)
• EPA Substance Registry System: 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER(57362-77-3)

Safety Data

• Hazardous Substances Data: 57362-77-3(Hazardous Substances Data)

Usage

General Description

4-Iodo-3-nitro-benzoic acid ethyl ester is a chemical compound with the molecular formula C9H8INO5. It is an ester derivative of 4-iodo-3-nitrobenzoic acid and is commonly used in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. 4-IODO-3-NITRO-BENZOIC ACID ETHYL ESTER is a pale yellow solid and is insoluble in water, but soluble in organic solvents such as ethanol and acetone. It is important to handle this compound with caution as it may be harmful if ingested, inhaled, or comes into contact with the skin.

Upstream product

• 64-17-5 ethanol 
• 35674-27-2 4-iodo-3-nitrobenzoic acid 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 619-58-9 4-iodobenzoic acid 
• 23239-88-5 benzocaine hydrochloride 
• 76918-64-4 ethyl 4-amino-3-nitrobenzoate 

Downstream Products

• 101420-88-6 4-iodo-3-nitrobenzaldehyde 
• 612825-76-0 5-hydroxymethyl-2-iodonitrobenzene 
• 1219744-26-9 C₁₂H₁₃NO₄ 
• 149913-93-9 6-ethoxycarbonyl-2-phenylindole 
• 51094-28-1 9H-carbazole-2-carboxylic acid 

Relevant articles and documents

Preparation of Functionalized Diorganomagnesium Reagents in Toluene via Bromine or Iodine/Magnesium-Exchange Reactions

A wide range of polyfunctionalized di(hetero)aryl- and dialkenyl-magnesium reagents are prepared in toluene within 10 to 120 minutes between 78 C and 25 C via an I/Mg- or Br/Mg-exchange reaction using reagents of the general formula R2Mg (R = sBu, Mes). Highly sensitive functional groups, such as triazene or nitro, are tolerated in these exchange reactions, enabling the synthesis of various functionalized (hetero)arene and alkene derivatives after quenching with several electrophiles including allyl bromides, acyl chlorides, aldehydes, ketones, and aryl iodides.

BENZAMIDE OR BENZAMINE COMPOUNDS USEFUL AS ANTICANCER AGENTS FOR THE TREATMENT OF HUMAN CANCERS

The described invention provides small molecule anti-cancer compounds for treating tumors that respond to cholesterol biosynthesis inhibition. The compounds selectively inhibit the cholesterol biosynthetic pathway in tumor-derived cancer cells, but do not

NOVEL CC-1065 ANALOGS AND THEIR CONJUGATES

This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.