57384-84-6

Basic information

• Product Name: 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-(phenylmethyl)-
• CAS NO: 57384-84-6
• Molecular Formula: C15H10ClNO3
• Molecular Weight: 287.702
• Mol File: 57384-84-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-(phenylmethyl)-(57384-84-6)
• EPA Substance Registry System: 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-(phenylmethyl)-(57384-84-6)

Safety Data

• Hazardous Substances Data: 57384-84-6(Hazardous Substances Data)

Upstream product

• 4743-17-3 5-Chloroisatoic anhydride 
• 620-05-3 iodomethylbenzene 
• 26960-68-9 1-benzyl-5-chloroisatin 
• 100-39-0 benzyl bromide 

Downstream Products

• 144129-01-1 10-Benzyl-7-chloro-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-2H,10H-acridine-1,9-dione 
• 77556-55-9 4-Benzyl-7-chloro-9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-2-carboxylic acid ethyl ester 
• 77422-96-9 4-Benzyl-7-chloro-9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-2-carboxylic acid 
• 77423-05-3 4-Benzyl-7-chloro-9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-2-carboxylic acid (1H-tetrazol-5-yl)-amide 
• 1407753-35-8 C₂₆H₃₀ClN₃O₄ 
• 1407753-23-4 C₂₂H₂₃ClN₂O₂ 
• 1452386-65-0 13-benzyl-5-(tert-butylimino)-10-chloro-6-phenyl-5,6,13,13a-tetrahydro-8H-phthalazino[1,2-b]quinazolin-8-one 
• 1452386-66-1 13-benzyl-10-chloro-5-(cyclohexylimino)-6-phenyl-5,6,13,13a-tetrahydro-8H-phthalazino[1,2-b]quinazolin-8-one 
• 1452386-55-8 1-benzyl-2-(2-bromophenyl)-6-chloro-3-(phenylamino)-2,3-dihydroquinazolin-4(1H)-one 

Relevant articles and documents

Recyclable (PhSe)2-catalyzed selective oxidation of isatin by H2O2: a practical and waste-free access to isatoic anhydride under mild and neutral conditions

After a series of careful conditional optimizations and catalyst screenings, a methodology to prepare isatoic anhydrides through organoselenium-catalyzed selective oxidation of isatins by H2O2 under mild and neutral conditions was developed. The reactions were very practical because of the recyclability of the catalyst and solvent and the convenient isolation procedures of the products. This work reports the organoselenium-catalyzed oxidation of heterocycles that greatly expands the application scopes of organoselenium catalysis. It also indicates that the organoselenium catalysts are robust enough to be recycled in industrial production if suitable isolation procedures are developed.

INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures (Ia), (Ib) including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.

The chemistry of 2H 3,1 benzoxazine 2,4(1H)dione (isatoic anhydrides). I. The synthesis of N substituted 2H 3,1 benzoxazine 2,4(1H)diones

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