5739-38-8 Usage
Description
1-(4-methoxyphenyl)-3-phenyl-propan-1-one, also known as p-methoxyphenylacetone, is an organic compound with the molecular formula C16H16O2. It is a key intermediate in the synthesis of various pharmaceuticals and other organic compounds, particularly in the production of amphetamines and other psychoactive substances. This colorless liquid exhibits a sweet, floral odor and is characterized by its flammable nature and potential hazardous properties.
Uses
Used in Pharmaceutical Synthesis:
1-(4-methoxyphenyl)-3-phenyl-propan-1-one is used as a key intermediate in the pharmaceutical industry for the synthesis of various pharmaceuticals and organic compounds. Its role in the production process is crucial due to its ability to form the backbone of these compounds.
Used in the Production of Amphetamines:
In the chemical industry, 1-(4-methoxyphenyl)-3-phenyl-propan-1-one is used as a precursor in the production of amphetamines and other psychoactive substances. Its chemical structure allows for further modification and synthesis into these compounds.
Used in Research and Development:
1-(4-methoxyphenyl)-3-phenyl-propan-1-one is also utilized in the research and development sector for studying the properties and potential applications of ketone functional group compounds. Its unique structure makes it an interesting subject for scientific inquiry and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 5739-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,3 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5739-38:
(6*5)+(5*7)+(4*3)+(3*9)+(2*3)+(1*8)=118
118 % 10 = 8
So 5739-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-6,8-11H,7,12H2,1H3
5739-38-8Relevant articles and documents
Intramolecular Quenching of Carbonyl Triplets by β-Phenyl Rings
Wismontski-Knittel, T.,Kilp, T.
, p. 110 - 115 (1984)
The presence of a phenyl ring in a position β to the carbonyl of a phenyl alkyl ketone results in greatly reduced ketone triplet lifetimes.For example, in deaerated benzene solutions, triplet lifetimes were 2700 and 0.89 ns for propiophenone (P) and β-phe
Nickel-catalyzed α-alkylation of ketones with benzyl alcohols
Wu, Di,Wang, Yubin,Li, Min,Shi, Lei,Liu, Jichang,Liu, Ning
, (2021/11/04)
We reported an efficient method for α-alkylation of ketones with benzyl alcohols using the pyridine-bridged pincer-type N-heterocyclic carbenes nickel complexes as catalysts. A wide range of ketones and benzyl alcohols were efficiently converted into various alkylated products in moderate to high yields. In addition, these nickel complexes were also successfully applied for the synthesis of a wide range of quinoline derivatives.
Acylboronates in polarity-reversed generation of acyl palladium(II) intermediates
Trofimova, Alina,Holownia, Aleksandra,Tien, Chieh-Hung,?irvinskas, Martynas J.,Yudin, Andrei K.
supporting information, p. 3294 - 3299 (2021/05/07)
We report a catalytic cross-coupling process between aryl (pseudo)halides and boron-based acyl anion equivalents. This mode of acylboronate reactivity represents polarity reversal, which is supported by the observation of tetracoordinated boronate and acyl palladium(II) species by 11B, 31P NMR, and mass spectrometry. A broad scope of aliphatic and aromatic acylboronates has been examined, as well as a variety of aryl (pseudo)halides.
