57395-89-8

Basic information

• Product Name: 4-FLUOROPIPERIDINE HYDROCHLORIDE
• Synonyms: 4-Fluoropiperidine hydrochloride;4-Fluoropiperidine hydroc...;4-Fluoropipiridine;4-Fluoropiperidine HCl;Piperidine,4-fluoro-,hydrochloride(1:1)
• CAS NO: 57395-89-8
• Molecular Formula: C5H11ClFN
• Molecular Weight: 139.6
• Mol File: 57395-89-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 163-167 °C
• Appearance: /
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 4-FLUOROPIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUOROPIPERIDINE HYDROCHLORIDE(57395-89-8)
• EPA Substance Registry System: 4-FLUOROPIPERIDINE HYDROCHLORIDE(57395-89-8)

Safety Data

• Hazard Codes: Xn,C,Xi
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT, AIR SENSITIVE
• Hazardous Substances Data: 57395-89-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C5H10FN.ClH/c6-5-1-3-7-4-2-5;/h5,7H,1-4H2;1H

Upstream product

• 78197-27-0 4-fluoropiperidine 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Downstream Products

• 917356-74-2 4'-{[(3R)-3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carboxylic acid 
• 917356-68-4 4'-{[(3R)-3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carbonitrile 
• 917356-69-5 4'-{[(3S)-3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carbonitrile 
• 917357-28-9 4'-{[3-(4-fluoro-piperidin-1-yl)pyrrolidin-1-yl]sulfonyl}biphenyl-4-carbonitrile 
• 1611475-73-0 5-((benzyloxy)methyl)-2-butyl-7-(5-(4-fluoropiperidin-1-yl)pent-1-yn-1-yl)-6-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine 
• 1611475-66-1 5-((benzyloxy)methyl)-2-butyl-7-(6-(4-fluoropiperidin-1-yl)hex-1-yn-1-yl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 
• 477576-96-8 2-(4-fluoropiperidin-1-yl)acetonitrile 
• 477576-97-9 2-(4-fluoropiperidin-1-yl)ethanamine 

Relevant articles and documents

CYCLOHEXYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel cyclohexylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.