57415-36-8 Usage
Description
N-(2-pyridylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is a complex organic compound characterized by its white solid appearance. It is an impurity in the synthesis of Flecainide, a medication used to treat certain types of abnormal heart rhythms. N-(2-pyridylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is also utilized as a novel intermediate in the preparation of Flecainide, contributing to the development of pharmaceuticals for cardiovascular applications.
Uses
Used in Pharmaceutical Industry:
N-(2-pyridylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is used as an intermediate in the synthesis of Flecainide for the treatment of abnormal heart rhythms. Its role in the production process is crucial for creating an effective medication that can help manage and regulate heart conditions.
Used in Chemical Research:
As an impurity in the synthesis of Flecainide, N-(2-pyridylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is also used in chemical research to study the properties and behavior of complex organic compounds. This can lead to advancements in the understanding of chemical reactions and the development of new pharmaceutical compounds.
Used in Drug Development:
N-(2-pyridylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide is used as a novel intermediate in the preparation of Flecainide, which is an essential component in the development of new drugs for cardiovascular conditions. Its application in drug development can potentially lead to the creation of more effective medications with fewer side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 57415-36-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,1 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57415-36:
(7*5)+(6*7)+(5*4)+(4*1)+(3*5)+(2*3)+(1*6)=128
128 % 10 = 8
So 57415-36-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H14F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h1-7H,8-10H2,(H,25,26)
57415-36-8Relevant articles and documents
Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof
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Page/Page column 4; 7, (2008/12/04)
A process for the preparation of Flecainide acetate, its salts, in particular its pharmaceutically acceptable salts, and intermediates thereof is described wherein 2,5-dibromotoluene is used as a starting material. The method involves a technique for preparing the starting material 2,5-bis(2,2,2-trifluroethoxy)toluene in high yields by reacting 2,5-dibromotoluene with 2,2,2-trifluoroethanol in the presence of a base and a copper-containing catalyst.
α,α-dibromo-α-chloro-acetophenones as synthons
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, (2008/06/13)
This disclosure relates to the use of α,α-dibromo-α-chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-α,α-dibromo-α-chloroacetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical.
Process for the preparation of derivatives of piperidine
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, (2008/06/13)
Processes for the preparation of the antiarrhythmic agent 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide.
