575484-83-2

Basic information

• Product Name: 6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
• Synonyms: 6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one;6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one;6-[(2-Chloro-5-fluoro-pyriMidin-4-yl)aMino]-2,2-diMethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
• CAS NO: 575484-83-2
• Molecular Formula: C₁₃H₁₁ClFN₅O₂
• Molecular Weight: 323.7101432
• Mol File: 575484-83-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 523.3°C at 760 mmHg
• Flash Point: 270.3°C
• Appearance: /
• Density: 1.470±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 4.78E-11mmHg at 25°C
• Refractive Index: 1.614
• PKA: 10.61±0.40(Predicted)
• CAS DataBase Reference: 6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one(575484-83-2)
• EPA Substance Registry System: 6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one(575484-83-2)

Safety Data

• Hazardous Substances Data: 575484-83-2(Hazardous Substances Data)

Usage

General Description

6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is a chemical compound with a complex structure that contains a pyrimidine ring, a pyridine ring, and an oxazin ring. It is a synthetic organic compound with potential pharmaceutical applications, although its specific uses are not immediately apparent. The presence of chloro and fluoro substituents on the pyrimidine ring suggests that it may have biological activity, and the presence of the oxazin ring indicates that it may have potential as a heterocyclic compound for medicinal chemistry research. However, further study would be needed to determine the specific properties and applications of this compound.

InChI:InChI=1/C13H11ClFN5O2/c1-13(2)11(21)19-10-7(22-13)3-4-8(18-10)17-9-6(15)5-16-12(14)20-9/h3-5H,1-2H3,(H2,16,17,18,19,20,21)

Upstream product

• 1002726-62-6 6-amino-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 
• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 

Downstream Products

• 841290-80-0 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 
• 901119-38-8 N₄-(2,2-dimethyl-4-[(di-tert-butyl-phosphonoxy)methyl]-3-oxo-5-pyrido[1,4]oxazin-6-yl)-5-fluoro-N₂-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine 
• 1260832-50-5 N₄-[2,2-dimethyl-3-oxo-pyrid[1,4]oxazin-6-yl]-5-fluoro-N₂-(3,4-dimethoxyphenyl-5-trideuteromethoxy)-2,4-pyrimidinediamine 

Relevant articles and documents

Pharmaceutical Process and Intermediates

The present disclosure provides for processes and intermediates in the large-scale manufacture of the compound of formula (I) or hydrates thereof.