57653-36-8 Usage
Molecular weight
381.46 g/mol The sum of the atomic weights of all the atoms in the compound.
Functional groups
Pyrrolidinecarboxylic acid, hydroxymethyl, sulfonyl, phenylmethyl ester The compound contains various functional groups that contribute to its chemical properties and reactivity.
Pyrrolidinecarboxylic acid
A five-membered nitrogen-containing ring with a carboxyl group (-COOH) attached.
Hydroxymethyl
A -CH2OH group, which contains a hydroxyl group (-OH) bonded to a methyl group (-CH3).
Sulfonyl
An -SO2 group, consisting of a sulfur atom double-bonded to two oxygen atoms.
Phenylmethyl ester
A phenyl group (a six-membered carbon ring with a single bond to a methyl group) bonded to a carbonyl group (C=O) through an ester linkage (-CO-).
Stereochemistry
2S,4R configuration The compound has a specific three-dimensional arrangement of its atoms, which is important for its biological activity and reactivity.
2S
The hydroxymethyl group is attached to the second carbon atom in a "south" (S) configuration, meaning it is below the plane of the pyrrolidine ring when viewed from the nitrogen atom.
4R
The phenylmethyl ester group is attached to the fourth carbon atom in a "right" (R) configuration, meaning it is on the right side of the molecule when viewed from the nitrogen atom.
Potential applications
Pharmaceutical or organic synthesis Due to its unique structure and potential reactivity, this compound may be useful in the development of new drugs or as an intermediate in organic synthesis.
Complexity
Complex chemical compound The presence of multiple functional groups and stereochemistry makes this compound complex and potentially interesting for further study and development.
Check Digit Verification of cas no
The CAS Registry Mumber 57653-36-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,5 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57653-36:
(7*5)+(6*7)+(5*6)+(4*5)+(3*3)+(2*3)+(1*6)=148
148 % 10 = 8
So 57653-36-8 is a valid CAS Registry Number.
57653-36-8Relevant articles and documents
An improved synthesis of (lS,4S)-2-oxa-5-azabicyclo[2.2.1]heptane
Zhang, Dong-Feng,Li, Peng,Lin, Zi-Yun,Huang, Hai-Hong
, p. 479 - 481 (2014/03/21)
An improved and efficient method for synthesis of (lS,4S)-2-oxa-5- azabicyclo[2.2.1]heptane (1) from trans-4-hydroxy-l-proline was developed. Using benzyloxycarbonyl (Cbz) as protection group of amine, the reactions were in mild conditions, and the title compound 1 was accomplished in six steps in overall yield of 70%.
Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses
-
Page 210, (2010/11/30)
Compounds having activity against production of an inflammatory cytokine of formula (I)′: 1A′ is pyrrole; R1′ is phenyl or naphthyl; R2′ is pyridyl or pyrimidinyl; R3′ is (IIa)′, (IIb)′ or (IIc)′: 2m′ is 1; E′ is nitrogen; D′ is >C(R5′)—, R5′ is hydrogen, Substituent α′ or Substituent β′; B′ is nitrogen-containing 5-membered heterocyclic; R4′ is 1 to 3 substituents from Substituent α′, Substituent β′ and Substituent γ′; R1′ and R3′ are bonded to two atoms of the pyrrole adjacent to the pyrrole atom bonded to R2′; Substituent α′ is hydroxyl, nitro, cyano, halogen, alkoxy, halogeno alkoxy, alkylthio, halogeno alkylthio or —NRa′Rb′; Ra′ and Rb′ are hydrogen, alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl, or Ra′ and Rb′ with the nitrogen atom form a heterocyclyl; Substituent β′ is alkyl, alkenyl, alkynyl, aralkyl or cycloalkyl; Substituent γ′ is oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, aryl, aryloxy, alkylidenyl or aralkylidenyl.
