57711-44-1 Usage
Description
3β-tert-ButyldiMethylsilyloxy Epiandrosterone is a synthetic derivative of the steroid hormone Epiandrosterone, which is naturally present in human urine. It is characterized by the presence of a tert-butyldimethylsilyloxy group at the 3β position, which distinguishes it from its less active 3β-isomer, Androsterone. 3β-tert-ButyldiMethylsilyloxy Epiandrosterone is a white solid and is classified as a controlled substance due to its potential applications in the synthesis of other steroids.
Uses
Used in Pharmaceutical Industry:
3β-tert-ButyldiMethylsilyloxy Epiandrosterone is used as an intermediate in the synthesis of various steroidal compounds for pharmaceutical applications. Its unique chemical structure allows for the development of new drugs with potential therapeutic benefits in treating hormonal disorders, inflammation, and other conditions related to steroid hormone imbalances.
Used in Research and Development:
In the field of research and development, 3β-tert-ButyldiMethylsilyloxy Epiandrosterone serves as a valuable tool for studying the structure-activity relationships of steroid hormones and their analogs. This knowledge can be applied to design and develop novel steroidal compounds with improved pharmacological properties and reduced side effects.
Used in Analytical Chemistry:
3β-tert-ButyldiMethylsilyloxy Epiandrosterone can be employed as a reference compound in analytical chemistry for the development and validation of methods for the detection and quantification of steroid hormones and their metabolites in biological samples. This is particularly relevant in the fields of sports doping control, endocrinology, and toxicology.
Used in Drug Delivery Systems:
Similar to Gallotannin, 3β-tert-ButyldiMethylsilyloxy Epiandrosterone can be incorporated into drug delivery systems to improve its bioavailability and therapeutic efficacy. By using various organic and metallic nanoparticles as carriers, the compound can be delivered more effectively to target tissues, enhancing its potential applications in the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 57711-44-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,7,1 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 57711-44:
(7*5)+(6*7)+(5*7)+(4*1)+(3*1)+(2*4)+(1*4)=131
131 % 10 = 1
So 57711-44-1 is a valid CAS Registry Number.
57711-44-1Relevant articles and documents
Macrocyclic molecular rotors with bridged steroidal frameworks
Czajkowska-Szczykowska, Dorota,Rodriguez-Molina, Braulio,Magana-Vergara, Nancy E.,Santillan, Rosa,Morzycki, Jacek W.,Garcia-Garibay, Miguel A.
, p. 9970 - 9978 (2012)
In this work, we describe the synthesis and solid-state dynamics of isomeric molecular rotors 7E and 7Z, consisting of two androstane steroidal frameworks linked by the D rings by triple bonds at their C17 positions to a 1,4-phenylene rotator. They are also linked by the A rings by an alkenyl diester bridge to restrict the conformational flexibility of the molecules and reduce the number of potential crystalline arrays. The analysis of the resulting molecular structures and packing motifs offered insights of the internal dynamics that were later elucidated by means of line shape analyses of the spectral features obtained through variable-temperature solid-state 13C NMR; such analysis revealed rotations in the solid state occurring at kilohertz frequency at room temperature.
Catalyst-free and metal-free electrophilic bromoamidation of unactivated olefins using the N-bromosuccinimide/sulfonamide Protocol
Yu, Wesley Zongrong,Chen, Feng,Cheng, Yi An,Yeung, Ying-Yeung
, p. 2815 - 2821 (2015/03/18)
An efficient, catalyst-free, and metal-free bromoamidation of unactivated olefins has been developed. 4-(Trifluoromethyl)benzenesulfonamide and N-bromosuccinimide were used as the nitrogen and halogen sources, respectively. The methodology is applicable to both cyclic and aliphatic olefins.
First synthesis of a pentadeuterated 3′-hydroxystanozolol - An internal standard in doping analysis
Felzmann, Wolfgang,Gmeiner, Günter,G?rtner, Peter
, p. 103 - 110 (2007/10/03)
The first synthesis of 16,16,20,20,20-pentadeuterio-3′- hydroxystanozolol (8) in 26% yield over nine steps is described using moderately priced starting materials and economic amounts of reagents. Compound 8 can be used as an internal standard in screening procedures for anabolic steroids as well as for the quantification of stanozolol metabolites via mass spectrometric techniques, such as LC-MS or gas chromatography-mass spectrometry (GC-MS).
