57734-44-8

Basic information

• Product Name: (1-benzylpyrrolidin-2-yl)methanamine
• Synonyms: (1-benzylpyrrolidin-2-yl)methanamine;2-PyrrolidineMethanaMine, 1-(phenylMethyl)-
• CAS NO: 57734-44-8
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.28472
• Mol File: 57734-44-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1-benzylpyrrolidin-2-yl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1-benzylpyrrolidin-2-yl)methanamine(57734-44-8)
• EPA Substance Registry System: (1-benzylpyrrolidin-2-yl)methanamine(57734-44-8)

Safety Data

• Hazardous Substances Data: 57734-44-8(Hazardous Substances Data)

Usage

General Description

(1-benzylpyrrolidin-2-yl)methanamine is a chemical compound with the molecular formula C13H18N2. It is a derivative of pyrrolidine with a benzyl group attached to the nitrogen atom. (1-benzylpyrrolidin-2-yl)methanamine has been studied for its potential therapeutic effects, particularly as a psychoactive substance. It may act as a selective dopamine reuptake inhibitor and could have potential applications in the treatment of psychiatric disorders or addiction. However, (1-benzylpyrrolidin-2-yl)methanamine is also known to have psychoactive effects and has been identified as a designer drug, leading to its classification as a controlled substance in some jurisdictions. Research into the pharmacological properties and potential risks associated with this compound is ongoing.

Upstream product

• 60169-70-2 1-benzylpyrrolidine-2-carboxamide 
• 60169-68-8 2-azidomethyl-1-benzylpyrrolidine 
• 1227866-76-3 methanesulfonic acid (1-benzyl-piperidin-3-yl)methyl ester 
• 14813-01-5 1-benzyl-3-hydroxypiperidine 
• 6859-99-0 3-hydroxypiperazine 
• 100-52-7 benzaldehyde 
• 1148-11-4 N-carbobenzyloxyproline 
• 93188-01-3 2-(aminocarbonyl)-1-pyrrolidinecarboxylic acid, phenylmethyl ester 
• 2812-47-7 pyrrolidine-2-carboxylic acid amide 
• 201406-78-2 1-benzylpyrrolidine-2-carboxylic acid methyl ester 
• 60169-72-4 1-benzyl-pyrrolidine-2-carboxylic acid 

Downstream Products

• 149649-57-0 (N-tert-butoxycarbonylaminomethyl)-N-benzylpyrrolidine 
• 60737-17-9 N-(1-benzyl-pyrrolidin-2-ylmethyl)-formamide 
• 84332-25-2 4-Methoxy-2-methylamino-pyrimidine-5-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide; hydrochloride 
• 121998-21-8 1-benzyl-2-<(trifluoroacetylamino)methyl>pyrrolidine 
• 84332-26-3 2-Dimethylamino-4-methoxy-pyrimidine-5-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide; hydrochloride 
• 72412-48-7 2-Amino-4-methoxy-pyrimidine-5-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide 
• 82689-90-5 N-(1-Benzyl-pyrrolidin-2-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide 
• 132020-42-9 N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2-hydroxy-6-methoxy-benzamide 
• 96695-98-6 N-(1-benzyl-2-pyrrolidinylmethyl)-2-methyl-5-sulfamoyl-2,3-dihydrobenzofuran-7-carboxamide 

Relevant articles and documents

PYRIDINE-3-CARBOXYAMIDE DERIVATIVE

To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sj?gren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.

N-(1-benzyl pyrrolidinyl 2-alkyl) substituted benzamides and derivatives thereof

The benzamides of this invention and their pharmaceutically acceptable salts are particularly effective in the treatment of emesis and ulcers in mammals. Their low level of toxicity is compatible with use in human therapy, without undesirable side effects.