57812-20-1

Basic information

• Product Name: Ruthenium, hydroiodotris(triphenylphosphine)-
• CAS NO: 57812-20-1
• Molecular Formula: C54H46IP3Ru
• Molecular Weight: 1015.86
• Mol File: 57812-20-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ruthenium, hydroiodotris(triphenylphosphine)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ruthenium, hydroiodotris(triphenylphosphine)-(57812-20-1)
• EPA Substance Registry System: Ruthenium, hydroiodotris(triphenylphosphine)-(57812-20-1)

Safety Data

• Hazardous Substances Data: 57812-20-1(Hazardous Substances Data)

Upstream product

• 15529-49-4 tris(triphenylphosphine)ruthenium(II) chloride 
• 7681-82-5 sodium iodide 
• 591-50-4 iodobenzene 
• 36620-55-0 {Ru(hydrogen)2(nitrogen)(triphenylphosphine)3} 
• 7681-65-4 copper(l) iodide 
• 7732-18-5 water 
• 138614-14-9 mer-hydrido[[(ethoxycarbonyl)methyl]cyano](ethyl cyanoacetate)tris(triphenylphosphine)ruthenium(II) 
• 74-88-4 methyl iodide 

Downstream Products

• 14564-35-3 cis-[RuCl₂(CO)2(PPh₃)2] 

Relevant articles and documents

Mild, Selective Ru-Catalyzed Deuteration Using D2O as a Deuterium Source

A method for the selective deuteration of polyfunctional organic molecules using catalytic amounts of [RuCl2(PPh3)3] and D2O as a deuterium source is presented. Through variation of additives like CuI, KOH, and various amounts of zinc powder, orthogonal chemoselectivities in the deuteration process are observed. Mechanistic investigation indicates the presence of different, defined Ru-complexes under the given specific conditions.

Ruthenium-catalyzed aldol and Michael reactions of nitriles. Carbon-carbon bond formation by α-C-H activation of nitriles

The ruthenium(II)-catalyzed reaction of nitriles with carbonyl compounds proceeds highly efficiently under neutral and mild conditions to give α,β-unsaturated nitriles. Under similar reaction conditions, nitriles react with olefins bearing electron-withdrawing groups to give the corresponding Michael adducts. The efficiency of the reaction is illustrated by the selective additions to α,β-unsaturated aldehydes and acetylenes bearing electron-withdrawing groups, which are difficult to perform using conventional bases. Chemoselective aldol and Michael reactions of nitriles can be performed in the presence of other active methylene compounds. Tandem Michael and Michael-aldol condensations of nitriles 30 can be performed with high diastereoselectivity. These reactions can be rationalized by assuming oxidative addition of ruthenium(0) to the α-C-H bond of nitriles and subsequent insertions to carbonyl compounds or olefins. As the key intermediates and active catalysts hydrido(N-bonded enolato)ruthenium(II) complexes, mer-RuH(NCCHCO2R)(NCCH2CO2R)(PPh3)3 (R = Me (41a), Et (41b), n-Bu (41c)) have been isolated upon treatment of RuH2(PPh3)4 (3) or RuH(C2H4)(PPh3)2(PPh2C6H4) (4) with alkyl cyanoacetates. Kinetic study of the catalytic aldol reaction of ethyl cyanoacetate with benzaldehyde indicates that the rate-determining step is the reaction of enolato complex 41 with aldehydes.