57854-49-6

Basic information

• Product Name: Benzenepropanamide, 3-methoxy-
• CAS NO: 57854-49-6
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.219
• Mol File: 57854-49-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, 3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, 3-methoxy-(57854-49-6)
• EPA Substance Registry System: Benzenepropanamide, 3-methoxy-(57854-49-6)

Safety Data

• Hazardous Substances Data: 57854-49-6(Hazardous Substances Data)

Upstream product

• 6971-51-3 3-methoxybenzyl alcohol 
• 75-05-8 acetonitrile 
• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 
• 40478-49-7 3-(3-methoxyphenyl)propanoyl chloride 

Downstream Products

• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 42923-77-3 6-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 18655-52-2 3-(3-methoxyphenyl)propan-1-amine 
• 1400705-43-2 2-[3-(3-methoxyphenyl)propylamino]-4,6-dimethylpyrimidine-5-carboxylic acid ethyl ester 
• 1400705-44-3 2-[3-(3-hydroxyphenyl)propylamino]-4,6-dimethylpyrimidine-5-carboxylic acid ethyl ester 
• 1400705-91-0 2-[3-(3-methoxy-phenyl)propylamino]-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester 
• 1400705-92-1 2-[3-(3-hydroxy-phenyl)propylamino]-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester 
• 1400705-93-2 2-[3-(3-hydroxy-phenyl)propylamino]-4-trifluoromethyl-pyrimidine-5-carboxylic acid 
• 1400706-03-7 (S)-3-tert-butoxycarbonylamino-2-({2-[3-(3-hydroxy-phenyl)propylamino]pyrimidine-5-carbonyl}amino)propionic acid methyl ester 
• 1400706-05-9 (S)-3-tert-butoxycarbonylamino-2-({2-[3-(3-hydroxy-phenyl)propylamino]-4-trifluoromethyl-pyrimidine-5-carbonyl}amino)propionic acid methyl ester 
• 1400704-36-0 (S)-2-({2-[3-(3-hydroxy-phenyl)propylamino]pyrimidine-5-carbonyl}amino)-3-[(thiophene-2-carbonyl)amino]propionic acid methyl ester 
• 1400704-38-2 (S)-2-({2-[3-(3-hydroxy-phenyl)propylamino]-4-trifluoromethyl-pyrimidine-5-carbonyl}amino)-3-[(thiophene-2-carbonyl)amino]propionic acid methyl ester 
• 1400705-40-9 2-[3-(3-methoxy-phenyl)propylamino]pyrimidine-5-carboxylic acid methyl ester 
• 1400705-41-0 2-(3-(3-hydroxy-phenyl)propylamino)pyrimidine-5-carboxylic acid methyl ester 

Relevant articles and documents

Base-controlled chemoselectivity: direct coupling of alcohols and acetonitriles to synthesise α-alkylated arylacetonitriles or acetamides

We achieved chemoselective synthesis of α-alkylated arylacetonitriles and acetamides by combining Ir complex-catalysed direct coupling of alcohols and nitriles by a simple adjustment of the base. Methanol and ethanol performed well as the alkylating reagents. This method of acetonitrile alkylation provided a novel approach for carbon chain extension.

PYRIMIDINE AMIDE COMPOUNDS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.