578700-80-8

Basic information

• Product Name: N-(2-benzoyl-4-nitrophenyl)-2-(4-methyl-1-piperazinyl)acetamide
• CAS NO: 578700-80-8
• Molecular Weight: 382.419
• Mol File: 578700-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-benzoyl-4-nitrophenyl)-2-(4-methyl-1-piperazinyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-benzoyl-4-nitrophenyl)-2-(4-methyl-1-piperazinyl)acetamide(578700-80-8)
• EPA Substance Registry System: N-(2-benzoyl-4-nitrophenyl)-2-(4-methyl-1-piperazinyl)acetamide(578700-80-8)

Safety Data

• Hazardous Substances Data: 578700-80-8(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 20821-91-4 N-(2-benzoyl-4-nitrophenyl)-2-chloroacetamide 

Relevant articles and documents

Antimalarial and antitrypanosomal activity of a series of amide and sulfonamide derivatives of a 2,5-diaminobenzophenone

Here, we describe a series of readily obtainable benzophenone derivatives with antimalarial and antitrypanosomal activity. The most active compounds display submicromolar activity against Plasmodium falciparum. Micromolar activity is obtained against Trypanosoma brucei. Main problem of the compounds is low selectivity. However, there are indications that separation of antimalarial and cytotoxic activity might by possible. In addition, some compounds inhibit human ABC transporter with nanomolar activity.