57897-77-5Relevant articles and documents
Correlation of the rates of Solvolysis of 2,1-benzoxathiol-3-one-1, 1-dioxide (2-sulfobenzoic acid cyclic anhydride)
Kevill, Dennis N.,Ryu, Zoon Ha
, p. 561 - 566 (2015)
Solvolysis of acyclic mixed carboxylic-sulfonic anhydrides in hydroxylic solvents is known to involve displacement at the carbonyl carbon to produce a carboxylic acid (water as the nucleophile) and/or an ester (alcohol as the nucleophile) plus the anion of the sulfonic acid. Parallel solvolyses of the cyclic mixed anhydride 2-sulfobenzoic anhydride (structurally similar to phthalic anhydride but with one carbonyl group replaced by a sulfonyl group) involve expulsion from the carbonyl carbon of a sulfonate anion that remains attached as an orthosubstituent in the benzoic acid and/or benzoate ester produced. This complicates the choice of a solvent-ionising-power scale for use in an extended Grunwald-Winstein equation treatment. The YOTs scale, previously recommended as a good general purpose scale, is chosen and used in conjunction with the NT solvent nucleophilicity scale. An acceptable correlation is obtained, which is improved when the two solvents rich in the highly ionising 1,1,1,3,3,3-hexafluoro-2-propanol are excluded. As the solvent is varied, the sensitivities to the changes induced in the two scales are low, consistent with an early transition state, but their ratio has a value which is typical for a pathway involving addition-elimination, with addition rate-determining. Earlier reports, supporting aspects of the proposed mechanism, are reviewed.
Aryl and alkyl sulfonic acid compounds as well as construction method adopting inorganic sulfur salt and application
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Paragraph 0046-0049; 0088-0091, (2020/09/16)
The invention discloses aryl and alkyl sulfonic acid compounds as shown in a formula (1) and a synthesis method thereof. The method comprises the following step: aromatic iodine and an inorganic sulfur source or alkyl bromide and an inorganic sulfur source as reaction raw materials react in a solvent under the action of alkali, a catalyst or an additive to obtain a series of aryl and alkyl sulfonic acid compounds. According to the method, the aryl and alkyl sulfonic acid compounds are constructed in one step by taking an inorganic sulfur reagent as a sulfur source, so that the defect of the mode in which the aryl and alkyl sulfonic acid compounds are synthesized by taking concentrated sulfuric acid, chlorosulfonic acid or sulfur dioxide gas and the like as sulfonating reagents in the priorart is avoided. The aryl and alkyl sulfonic acid compounds developed by the invention can be used for synthesizing aryl and alkyl sulfonic acid drug analogues.
Arylphosphonylation and arylazidation of activated alkenes
Kong, Wangqing,Merino, Estibaliz,Nevado, Cristina
supporting information, p. 5078 - 5082 (2014/05/20)
Two radical-mediated processes of activated alkenes, namely arylphosphonylation and arylazidation, are described. The difunctionalization of alkenes by a tandem process that involves radical addition, 1,4-aryl migration, and desulfonylation generates α-ar
