57928-92-4

Basic information

• Product Name: Benzonitrile, 4-[(4-cyanophenoxy)methyl]-
• CAS NO: 57928-92-4
• Molecular Formula: C15H10N2O
• Molecular Weight: 234.257
• Mol File: 57928-92-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[(4-cyanophenoxy)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[(4-cyanophenoxy)methyl]-(57928-92-4)
• EPA Substance Registry System: Benzonitrile, 4-[(4-cyanophenoxy)methyl]-(57928-92-4)

Safety Data

• Hazardous Substances Data: 57928-92-4(Hazardous Substances Data)

Upstream product

• 17201-43-3 4-cyanobenzyl bromide 
• 126747-14-6 4-cyanophenylboronic acid 
• 874-89-5 4-Cyanobenzyl alcohol 
• 767-00-0 4-cyanophenol 
• 123-30-8 4-amino-phenol 
• 874-86-2 4-cyanobenzyl chloride 

Downstream Products

• 1456777-87-9 4-N'-hydroxyamidinobenzyl 4-N'-hydroxyamidinophenyl ether 
• 56806-89-4 MC 96 

Relevant articles and documents

Pd(OAc)2-catalyzed synthesis of benzyl phenyl ether derivatives with H2O2 as an oxidant in neat water

A new protocol for Pd(OAc)2-catalyzed reactions of different benzyl bromides and various arylboronic acids has been developed to form functionalized benzyl phenyl ethers. This method represents the first instance where arylboronic acid is used as a reaction substrate for benzyl phenyl ether synthesis with H2O2 as the green oxidant under atmospheric oxygen and pure H2O as an environmental friendly solvent without the requirement for phosphine- and N-based ligands, remarkable functional group tolerance, and considerable yield.

Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives

Sixty-two cationic benzyl phenyl ether derivatives (36 amidines and 26 prodrugs) were prepared and assayed for activities in vitro and in vivo against Trypanosoma brucei rhodesiense (STIB900), and in vitro against Plasmodium falciparum (K1) and Leishmania