57943-60-9

Basic information

• Product Name: METHYL 4-HYDROXYBENZIMIDATE HYDRO-CHLORIDE
• Synonyms: Methyl 4-hydroxybenmidate hydrochloride;MHBI;WOOD'S REAGENT;METHYL P-HYROXYBENZIMIDATE HYDROCHLORIDE;METHYL 4-HYDROXYBENZIMIDATE HYDRO-CHLORIDE;methyl4-hydroxybenzimidateHCl;METHYL-P-HYDROXYBENZIMIDATEHYDROCHLORIDE;Methyl p-hydroxy-benzimidate
• CAS NO: 57943-60-9
• Molecular Formula: C₈H₉NO₂*ClH
• Molecular Weight: 187.62
• Mol File: 57943-60-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 174-180 °C (dec.)
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 4-HYDROXYBENZIMIDATE HYDRO-CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-HYDROXYBENZIMIDATE HYDRO-CHLORIDE(57943-60-9)
• EPA Substance Registry System: METHYL 4-HYDROXYBENZIMIDATE HYDRO-CHLORIDE(57943-60-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3-10-21
• Hazardous Substances Data: 57943-60-9(Hazardous Substances Data)

Upstream product

• 767-00-0 4-cyanophenol 
• 75-36-5 acetyl chloride 
• 67-56-1 methanol 

Downstream Products

• 106050-91-3 4-<5'-(4''-methylpiperazin-1''-yl)-1H-benzimidazol-2'-yl>phenol hydrochloride 
• 15535-98-5 p-hydroxybenzamidine 
• 38148-63-9 p-amidinophenol hydrochloride 
• 1448673-74-2 tert-butyl 2-[(4-hydroxyphenyl)(imino)methyl]hydrazinecarboxylate 
• 1448673-76-4 tert-butyl 2-[{4-[2-(aminooxy)ethoxy]phenyl}(imino)methyl]hydrazinecarboxylate 
• 1448673-75-3 tert-butyl 2-[(4-{2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]ethoxy}phenyl)(imino)methyl]hydrazinecarboxylate 
• 347165-36-0 ethyl 1-cyclohexyl-2-(4-hydroxyphenyl)-1H-benzimidazole-5-carboxylate 
• 84437-20-7 Benzoic acid 4-carbamimidoyl-2-nitro-phenyl ester 

Relevant articles and documents

VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule Vascular Adhesion Protein- 1 (VAP-1) modulator compositions, pharmaceutical compositions, the use and preparation thereof.

Synthesis and antibacterial activities of Yanglingmycin analogues

The synthesis of Yanglingmycin and its enantiomer, along with eighteen Yanglingmycin analogues is reported. The structures were confirmed mainly by analyses of NMR spectral data. Antibacterial activity assays showed that Yanglingmycin and some of its analogues exhibited significant antibacterial activities against two important agricultural pathogenic bacteria, Ralstonia solanacearum and Pseudomonas syringae pv. actinidiae, with minimum inhibitory concentration (MIC) values ranging from 3.91 to 15.62 μg/mL. The antibacterial activities exhibited by Yanglingmycin and its analogues are promising, suggesting potential in the development of compounds for novel bactericides.

Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole

A series of 1-cycloalkyl-2-phenyl-1H-benzimidazole-5-carboxylic acid derivatives was synthesized and evaluated for inhibitory activity against HCV NS5B RNA-dependent RNA polymerase (RdRp). A SAR study was performed and led to identify the 2-[(4-diarylmeth