57965-30-7 Usage
Description
(S)-(-)-Thiolactic Acid, also known as (2S)-2-Mercaptopropanoic Acid, is an organic compound that serves as an intermediate in the synthesis of various bioactive molecules. It is characterized by its unique thiol group and carboxylic acid functionality, which contribute to its diverse range of applications in different industries.
Uses
Used in Pharmaceutical Industry:
(S)-(-)-Thiolactic Acid is used as an intermediate for the synthesis of (R)-(+)-Thiolactomycin (T350880), a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). This application is significant because it targets the inhibition of mycolic acid synthesis, which is a major cell wall component of Mycobacterium tuberculosis, a bacterium responsible for tuberculosis.
Additionally, (S)-(-)-Thiolactic Acid is used as an inhibitor of D-Aspartate oxidase (DDO), an enzyme involved in the metabolism of D-aspartate. This application is relevant in the development of drugs targeting neurological disorders and other conditions related to D-aspartate metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 57965-30-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,6 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57965-30:
(7*5)+(6*7)+(5*9)+(4*6)+(3*5)+(2*3)+(1*0)=167
167 % 10 = 7
So 57965-30-7 is a valid CAS Registry Number.
57965-30-7Relevant articles and documents
COMPOUNDS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES
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Page/Page column 60, (2016/05/02)
The present invention relates to compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
