58001-39-1

Basic information

• Product Name: nicotinamide adenine dinucleotide
• CAS NO: 58001-39-1
• Molecular Weight: 663.431
• Mol File: 58001-39-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: nicotinamide adenine dinucleotide(CAS DataBase Reference)
• NIST Chemistry Reference: nicotinamide adenine dinucleotide(58001-39-1)
• EPA Substance Registry System: nicotinamide adenine dinucleotide(58001-39-1)

Safety Data

• Hazardous Substances Data: 58001-39-1(Hazardous Substances Data)

Upstream product

• 865-05-4 3-(aminocarbonyl)-1-[5-O-[[1-(6-amino-9H-purin-9-yl)-1-deoxy-β-D-ribofuranos-5-O-yl]phosphonyloxy(oxylato)phosphinyl]-β-L-ribofuranosyl]pyridinium 
• 58-68-4 nicotinamide adenine dinucleotide 
• 10012-96-1 C₂₁H₂₈⁽²⁾HN₇O₁₄P₂ 

Downstream Products

• 58-68-4 nicotinamide adenine dinucleotide 
• 29024-90-6 2-acetamido-2-deoxy-D-gluconic acid 

Relevant articles and documents

Mechanism of the Oxidation of NADH by Quinones. Energetics of One-Electron and Hydride Routes

The kinetics of NADH oxidation by 7 o-benzoquinones and 14 p-benzoquinones were studied by using buffered aqueous solutions and UV/vis spectroscopy.For each quinone the rate law was first order in NADH and first order in quinone.The rate constants varied from 0.0745 to 9220 M-1s-1.Variation of the pH from 6 to 8 gave no change in rate.The use of 4-D and 4,4-D2NADH revealed kinetic isotope effects.The dideutero data gave kH/kD in the range 1.6-3.1 for p-quinones and 4.2 for 3,5-di-tert-butyl-o-quinone.When p-quinones were used, the log k was a linear function of Eo for the quinone/hydroquinone monoanion (Q/QH(1-)) couple with a slope of 16.9 V-1. o-Quinones reacted about 100 times more rapidly, but the same linear relationship with a slope of 16.4 V-1 was observed.Comparisons to data for one-electron-transfer reactions indicate that such mechanisms are not involved.A hydride-transfer mechanism accommodates all the data, and rate-limiting hydrogen atom transfer followed by electron transfer cannot be ruled out.