58047-56-6

Basic information

• Product Name: 4-(2,4,6-trimethyl-benzoyl)-morpholine
• Synonyms: 4-(2,4,6-trimethyl-benzoyl)-morpholine
• CAS NO: 58047-56-6
• Molecular Weight: 233.31
• Mol File: 58047-56-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(2,4,6-trimethyl-benzoyl)-morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,4,6-trimethyl-benzoyl)-morpholine(58047-56-6)
• EPA Substance Registry System: 4-(2,4,6-trimethyl-benzoyl)-morpholine(58047-56-6)

Safety Data

• Hazardous Substances Data: 58047-56-6(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 201230-82-2 carbon monoxide 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 4028-63-1 iodomesitylene 

Relevant articles and documents

Direct Synthesis of Enamides via Electrophilic Activation of Amides

A novel, one-step N-dehydrogenation of amides to enamides is reported. This reaction employs the unlikely combination of LiHMDS and triflic anhydride, which serves as both the electrophilic activator and the oxidant, and is characterized by its simple setup and broad substrate scope. The synthetic utility of the formed enamides was readily demonstrated in a range of downstream transformations.

Highly efficient aminocarbonylation of iodoarenes at atmospheric pressure catalyzed by a robust acenaphthoimidazolyidene allylic palladium complex

A robust allylic palladium-NHC complex was developed and exhibited extremely high catalytic activity toward aminocarbonylation of various (hetero)aryl iodides under atmospheric carbon monoxide pressure, in which a broad range of secondary and primary amines were well tolerated. In addition, the concise synthesis of an anticancer drug tamibarotene was accomplished even in a gram scale, further highlighting the practical applicability of the protocol.