5805-58-3Relevant articles and documents
TRPC ION CHANNEL INHIBITORS FOR USE IN THERAPY
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Paragraph 00185, (2018/09/12)
Described herein are inhibitors of Transient Receptor Potential Canonical (TRPC) ion channels, comprising TRPC4 protein and/or TRPC5 protein, for use in combating obesity and other medical conditions, including insulin resistance associated with Type II diabetes or development of Type II diabetes (pre-diabetes), metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Also disclosed is the use of the inhibitors for cosmetic purposes, such as cosmetic weight loss.