5807-13-6

Basic information

• Product Name: (2Z)-2-({4-[chloro(difluoro)methoxy]phenyl}imino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide
• Synonyms: 2H-1,3-thiazine-6-carboxamide, 2-[[4-(chlorodifluoromethoxy)phenyl]imino]-N-(4-chlorophenyl)-3-ethyltetrahydro-4-oxo-, (2Z)-
• CAS NO: 5807-13-6
• Molecular Formula: C₂₀H₁₇Cl₂F₂N₃O₃S
• Molecular Weight: 488.3351
• Mol File: 5807-13-6.mol
• Article Data: 3

Chemical Properties

• Density: 1.46g/cm³
• Refractive Index: 1.621
• CAS DataBase Reference: (2Z)-2-({4-[chloro(difluoro)methoxy]phenyl}imino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-2-({4-[chloro(difluoro)methoxy]phenyl}imino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide(5807-13-6)
• EPA Substance Registry System: (2Z)-2-({4-[chloro(difluoro)methoxy]phenyl}imino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide(5807-13-6)

Safety Data

• Hazardous Substances Data: 5807-13-6(Hazardous Substances Data)

Usage

Description

(2Z)-2-(4-[chloro(difluoro)methoxy]phenylimino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide is a thiazinane derivative with a molecular formula C19H15Cl2F2N3O3S. It is a carboxamide compound with potential antineoplastic activity. This chemical may inhibit the growth and proliferation of cancer cells by interfering with the cell cycle and inducing apoptosis. Further research is needed to fully understand the pharmacological and toxicological properties of this compound.

Uses

Used in Pharmaceutical Industry:
(2Z)-2-(4-[chloro(difluoro)methoxy]phenylimino)-N-(4-chlorophenyl)-3-ethyl-4-oxo-1,3-thiazinane-6-carboxamide is used as a potential antineoplastic agent for the treatment of cancer. It may be effective in inhibiting the growth and proliferation of cancer cells by interfering with the cell cycle and inducing apoptosis. Further research is required to explore its full potential and understand its pharmacological and toxicological properties.

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Relevant articles and documents

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Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening

The oxidation reactions of 5-aminopyrimidine derivatives in dimethyl sulphoxide (DMSO) were studied. The DMSO solutions of the studied compounds became deeply coloured within a few hours or days. The oxidation products can undergo further condensation reactions with the starting pyrimidines to yield bipyrimidines and/or pyrimidopteridines. The reaction mechanism of the oxidation-condensation reaction was also supported by reactions of the 5-aminopyrimidines with alloxan (2,4,5,6-tetraoxopyrimidine). DMSO is often used as the solvent in in vitro tests of biological activities, but it is also an oxidising agent and may react with solute molecules and significantly affect the quality of the generated biochemical data.