58086-67-2 Usage
Description
2-Fluoro-1-methylpyridinium p-toluenesulfonate is an organic compound that serves as a reagent in the field of organic chemistry, particularly in peptide synthesis and the creation of certain ribonucleotides. It is known for its ability to facilitate the formation of peptide bonds and contribute to the synthesis of essential biological molecules.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-1-methylpyridinium p-toluenesulfonate is used as a peptide coupling reagent for the synthesis of various peptides. Its application is crucial in the development of new drugs and therapeutic agents, as peptides play a significant role in many biological processes and can be used to target specific diseases.
Used in Biochemical Research:
In the field of biochemical research, 2-Fluoro-1-methylpyridinium p-toluenesulfonate is utilized in the synthesis of specific ribonucleotides, which are the building blocks of RNA. This application is vital for understanding the structure and function of RNA molecules, as well as their role in gene expression and regulation.
Used in Chemical Synthesis:
2-Fluoro-1-methylpyridinium p-toluenesulfonate is also employed in various chemical synthesis processes, where it acts as a catalyst or reagent to facilitate the formation of desired products. Its use in this industry contributes to the development of new compounds and materials with potential applications in various fields, including materials science, electronics, and environmental science.
Check Digit Verification of cas no
The CAS Registry Mumber 58086-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,0,8 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 58086-67:
(7*5)+(6*8)+(5*0)+(4*8)+(3*6)+(2*6)+(1*7)=152
152 % 10 = 2
So 58086-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H8O3S.C6H7FN/c1-6-2-4-7(5-3-6)11(8,9)10;1-8-5-3-2-4-6(8)7/h2-5H,1H3,(H,8,9,10);2-5H,1H3/q;+1/p-1
58086-67-2Relevant articles and documents
Preparation of Mono-/Difluorinated Hydrocarbon Compounds
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Page/Page column 7-8, (2009/09/28)
Mono- or difluorinated hydrocarbon compounds are prepared from an alcohol or a carbonylated compound by reacting one of these with a fluorinating reagent, optionally in the presence of a base, the fluorinating agent comprising a pyridinium reactant having the following formula (F), wherein R0 is an alkyl or cycloalkyl radical:
Pseudo Vilsmeier reagents a new protocol for regiospecific C-C bond formation in pyridines
Yu, Chu-Yi,Taylor, David L.,Meth-Cohn, Otto
, p. 6661 - 6664 (2007/10/03)
2-Fluoro- and 2,6-difluoropyridine are readily quaternised with methyl p-toluenesulfonate and methyl triflate respectively. These salts readily undergo substitution of fluorine by enamines, the difluoro-derivatives being capable of specific mono- or disubstitution in a symmetrical or unsymmetrical manner. The products reduced to give keto-1, 2, 3, 6-tetrahydropyridines, can be hydrosed to the corresponding ketopyridines or hydrogenated to give ketopiperidines.
Method for preparing pharmacologically active cyanoguanidine derivative
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, (2008/06/13)
A pharmacologically active cyanoguanidine derivative, generally referred to as cimetidine, is prepared by causing 4-methyl-5-hydroxymethylimidazole or a salt thereof to react with 2-substituted-1-methyl pyridinium salt and then causing the intermediate reaction product to react with N-cyano-N'-methyl-N"-(2-melcaptoethyl)-guanidine. The initial and subsequent reactions are carried out at room temperature under atmospheric pressure, using one and the same reaction vessel. No isolation of the intermediate reaction product resulting from the first reaction is required preparatory to the subsequent reaction. The recovery of the final intended product is carried out without using a column chromatography.
