581076-63-3

Basic information

• Product Name: N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE
• Synonyms: N-(3-aMino-4-Methylphenyl) -4-((4-Methylpiperazin-1-yl) Methyl)benzaMide;N-(3-amino-4-methylphenyl)-4-[(4-methyl-1-piperazinyl)methyl]benzamide;N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE;N-(3-Amino-4-methyl-phenyl)-4-(4-methyl-piperazin-1-yl)-benzamide
• CAS NO: 581076-63-3
• Molecular Formula: C20H26N4O
• Molecular Weight: 338.44664
• Product Categories: Aromatics Compounds;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 581076-63-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 454.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.190±0.06 g/cm3(Predicted)
• Solubility: Chloroform
• PKA: 13.35±0.70(Predicted)
• CAS DataBase Reference: N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE(581076-63-3)
• EPA Substance Registry System: N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE(581076-63-3)

Safety Data

• Hazardous Substances Data: 581076-63-3(Hazardous Substances Data)

Usage

Description

N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE, also known as CAS# 581076-63-3, is a compound that is useful in organic synthesis. It is characterized by its yellowish-orange solid appearance.

Uses

Used in Organic Synthesis:
N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE is used as a synthetic building block for the creation of various organic compounds. Its unique structure allows it to be a valuable component in the synthesis of complex molecules, potentially leading to the development of new pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE is used as a key intermediate in the development of new drugs. Its specific chemical properties make it a promising candidate for the synthesis of novel therapeutic agents, potentially targeting a wide range of medical conditions.
Used in Research and Development:
N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE is also utilized in research and development settings, where it can be employed to study the properties and reactivity of similar compounds. This can lead to a better understanding of their potential applications and the discovery of new chemical reactions or processes.
Used in Chemical Analysis:
Due to its distinctive chemical properties, N-(4-METHYL-3-AMINOPHENYL)-4-(4-METHYLPIPERAZINOMETHYL)BENZAMIDE can be used in chemical analysis to identify and characterize other compounds. It may serve as a reference material or be involved in the development of new analytical methods, contributing to the advancement of chemical research and technology.

Upstream product

• 368879-17-8 4-[(4-methylpiperazin-1-yl)methyl]bromobenzene 
• 201230-82-2 carbon monoxide 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 314268-40-1 4-((4-methylpiperazin-1-yl)methyl)-benzoic acid methyl ester 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 1571-08-0 methyl 4-formylbenzoate 
• 119-32-4 4-Methyl-3-nitroanilin 
• 106261-48-7 4-(4-methylpiperazin-1-ylmethyl)benzoic acid 
• 619-66-9 4-Carboxybenzaldehyde 
• 581076-60-0 N-(4-methyl-3-nitrophenyl)-4-[(4-methylpiprazin-1-yl)methyl]benzamide 
• 109-01-3 1-methyl-piperazine 

Relevant articles and documents

N-phenyl-2-pyrimidine-amine derivatives

The present invention relates to novel amides and a process for preparing these amides.

AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS

The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.

GLEEVEC PROCESS

The invention provides a process for the production of a pharmaceutical intermediate compound in accordance with the following scheme (formula (I)), wherein R5 is any suitable substituent group; and Z is any suitable leaving group.