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58166-38-4

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58166-38-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 58166-38-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,1,6 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58166-38:
(7*5)+(6*8)+(5*1)+(4*6)+(3*6)+(2*3)+(1*8)=144
144 % 10 = 4
So 58166-38-4 is a valid CAS Registry Number.

58166-38-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-dimethyl-thiazolidine-4(R)-carboxylic acid

1.2 Other means of identification

Product number -
Other names (R)-2,2-dimethyl-thiazolidine-4-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58166-38-4 SDS

58166-38-4Relevant articles and documents

Improved method for synthesis of cysteine modified hyaluronic acid for in situ hydrogel formation

Zhang, Xin,Sun, Pengcheng,Huangshan, Lingzi,Hu, Bi-Huang,Messersmith, Phillip B.

, p. 9662 - 9665 (2015)

We developed a new strategy for the functionalization of hyaluronic acid by chemical modification of its C-6 hydroxyl groups through an ether bond to obtain a cysteine-hyaluronic acid conjugate. This conjugate is suitable to prepare injectable and in situ formed hydrogels cross-linked by native chemical ligation and Michael addition under mild conditions.

SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES

-

Page/Page column 17; 18, (2020/12/30)

The present disclosure relates generally to the field of polypeptide synthesis, and more particularly, to the solution phase synthesis of the Wnt hexapeptide Foxy-5 and protected derivatives and peptide fragments thereof.

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Sun, Aiming,Lu, Yang J.,Hu, Haipeng,Shoji, Mamoru,Liotta, Dennis C.,Snyder, James P.

scheme or table, p. 6627 - 6631 (2010/06/14)

A series of novel curcumin analogs, symmetrical dienones, were previously shown to possess cytotoxic, anti-angiogenic and anti-tumor activities. Analogs 1 (EF24) and 2 (EF31) share the dienone scaffold and serve as Michael acceptors. We propose that the anti-cancer effects of 1 and 2 are mediated in part by redox-mediated induction of apoptosis. In order to support this concept, 1 and 2 were treated with l-glutathione (GSH) and cysteine-containing dipeptides under mild conditions to form colorless water-soluble adducts, which were identified by LC/MS. Comparison of the cytotoxic action of 1, 2 and the corresponding conjugates, 1-(GSH)2 and 2-(GSH)2, illustrated that the two classes of compounds exhibit essentially identical cell killing capabilities. Compared with the yellow, somewhat light sensitive and nearly water insoluble compounds 1 and 2, the glutathione conjugates represent a promising new series of stable and soluble anti-tumor pro-drugs.

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