58185-54-9Relevant articles and documents
Polymer network formation using the phosphane-ene reaction: A thiol-ene analogue with diverse postpolymerization chemistry
Guterman, Ryan,Rabiee Kenaree, Amir,Gilroy, Joe B.,Gillies, Elizabeth R.,Ragogna, Paul J.
, p. 1412 - 1419 (2015)
Air-stable primary phosphines were photopolymerized using phosphane-ene chemistry, the phosphorus analogue of the thiol-ene reaction, to fabricate a completely new class of polymer networks. It was demonstrated that the tunable thermal and physical properties accessible using thiol-ene chemistry could also be achieved using an analogous phosphane-ene reaction. At the same time, the presence of the 31P nucleus that is easily observed using NMR spectroscopy allowed the chemical structures of the networks to be directly probed using solid state NMR spectroscopy. Following its incorporation into the network, phosphorus offers the distinct difference and advantage of being able to undergo a diverse array of further derivatization to afford functional materials. For example, the networks were demonstrated to serve as effective oxygen scavengers and to bind transition metals (e.g., Pd). By using the air stable ferrocenyl phosphine (FcCH2CH2)PH2, redox-active networks were produced and these materials could be pyrolyzed to yield magnetic ceramics. Overall, this demonstrates the promise of phosphane-ene chemistry as an alternative to thiol-ene systems for providing functional materials for a diverse range of applications.
Application of HPLC for the screening of separation of new macrocyclic systems
Stefaniak, Monika,Romański, Jaros?aw
, p. 245 - 248 (2017/01/22)
The efficient synthesis of new macrocyclic systems via nucleophilic ring opening reaction of epoxides by thiols was described. Initially new macrocyclic compounds were obtained as a mixture of diastereomers. Preparative thin layer chromatography was applied to separate meso and pairs of enantiomer. The identification of products using a chiral HPLC column and mass spectroscopy was utilized.
Phototriggering of cell adhesion by caged cyclic RGD peptides
Petersen, Svea,Alonso, Jose Maria,Specht, Alexandre,Duodu, Portia,Goeldner, Maurice,Del Campo, Aranzazu
, p. 3192 - 3195 (2008/12/23)
Restrained potential: A caged cyclic peptide attached to a surface is able to trigger cell attachment to the surface with spatiotemporal definition upon exposure to light (λ = 351 nm). The peptide shows no integrin-binding activity in its caged form, but mediates cell adhesion effectively after irradiation (see optical microscopy image of cells on a surface irradiated through a mask in bands 100 μm in width). (Figure Presented).
