58186-26-8

Basic information

• Product Name: 1,4-Benzenediol, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
• CAS NO: 58186-26-8
• Molecular Formula: C19H32O5
• Molecular Weight: 340.46
• Mol File: 58186-26-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,4-Benzenediol, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenediol, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-(58186-26-8)
• EPA Substance Registry System: 1,4-Benzenediol, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-(58186-26-8)

Safety Data

• Hazardous Substances Data: 58186-26-8(Hazardous Substances Data)

Usage

Structure

Benzene ring with two hydroxyl groups, two methoxy groups, and a 10-carbon hydroxydecyl side chain

Classification

Phenol derivative

Amphiphilic properties

Presence of hydroxyl and methoxy groups

Applications

Personal care products (cosmetics, skin care items)

Moisturizing properties

Enhances skin hydration

Emulsifying properties

Helps blend water and oil in formulations

Synthesis

Used as a building block for various organic compounds

Manufacturing industry

Versatile and valuable chemical for production processes

Upstream product

• 58186-02-0 2,3-dimethoxy-5-methyl-6-(9'-methoxycarbonylnonyl)-1,4-benzoquinone 
• 58186-27-9 Idebenone 

Downstream Products

• 1431987-52-8 di-tert-butyl 2-(10-hydroxyundecyl)-5,6-dimethoxy-3-methyl-1,4-phenylene dicarbonate 
• 1431987-51-7 di-tert-butyl 2,3-dimethoxy-5-methyl-6-(10-oxodecyl)-1,4-phenylene dicarbonate 
• 1431987-02-8 11-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dienyl)undecan-2-yl nitrate 
• 1431987-50-6 di-tert-butyl 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-phenylene dicarbonate 
• 99590-14-4 1,2,3,4-tetramethoxy-6-(10-methoxydecyl)-5-methylbenzene 

Relevant articles and documents

Determination of idebenone in plasma by HPLC with post-column fluorescence derivatization using 2-cyanoacetamide

Idebenone is a benzoquinone analog that is used in the treatment of several neurological disorders including Friedreich's ataxia. It was found that the reaction of idebenone with 2-cyanoacetamide under alkaline conditions generates fluorescent products, a

A strategy for suppressing redox stress within mitochondria

An aza analogue (1) of the experimental neuroprotective drug idebenone has been prepared and evaluated. The compound quenches lipid peroxidation more effectively than α-tocopherol and potently suppresses reactive oxygen species in cells under oxidative stress. It is thought to do so via a catalytic cycle in which both forms of oxidative stress are suppressed simultaneously. Consequently, the compound effectively protects cultured CEM leukemia cells and Friedreich's ataxia fibroblasts from oxidative stress more effectively than idebenone or idebenol.

Aralkyl carboxylic acid compounds

Novel compounds of the formulae STR1 wherein R represents lower alkyl or lower alkoxy, A represents --CH2 --, --CO-- or STR2 n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.