582289-85-8 Usage
Description
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde is a complex organic compound characterized by its unique structure and functional groups. It is a synthetic intermediate with potential applications in various fields due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde is used as an intermediate in the synthesis of Dopal (D533885), which is the reactive metabolite of dopamine (D533780). Dopamine is an endogenous catecholamine with α and β-adrenergic activity, playing a crucial role in the regulation of various physiological processes, including the central nervous system, cardiovascular system, and renal function. 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde's role in the synthesis of Dopal highlights its importance in the development of pharmaceuticals targeting these systems.
Additionally, given its structural complexity and reactivity, 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde may have potential applications in other areas of the pharmaceutical industry, such as the development of novel drugs or drug delivery systems. However, further research and development would be required to explore these possibilities fully.
Check Digit Verification of cas no
The CAS Registry Mumber 582289-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,2,2,8 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 582289-85:
(8*5)+(7*8)+(6*2)+(5*2)+(4*8)+(3*9)+(2*8)+(1*5)=198
198 % 10 = 8
So 582289-85-8 is a valid CAS Registry Number.
582289-85-8Relevant articles and documents
Structure–Activity Relationship of Anti-malarial Allylpyrocatechol Isolated from Piper betle
Horii, Toshihiro,Itagaki, Sawako,Kawano, Tomikazu,Miyoshi, Akihito,Murakami, Nobutoshi,Tamura, Satoru
, p. 784 - 790 (2020/09/18)
Malaria disease remains a serious worldwide health problem. In South-East Asia, one of the malaria infection “hot-spots,” medicinal plants such as Piper betle have traditionally been used for the treatment of malaria, and allylpyrocatechol (1), a constituent of P. betle, has been shown to exhibit anti-malarial activities. In this study, we verified that 1 showed in vivo anti-malarial activity through not only intraperitoneal (i.p.) but also peroral (p.o.) administration. Additionally, some analogs of 1 were synthesized and the structure–activity relationship was analyzed to disclose the crucial sub-structures for the potent activity.