582333-68-4

Basic information

• Product Name: 3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-3-(1,8-naphthyridin-2-yl)-
• CAS NO: 582333-68-4
• Molecular Formula: C20H19N3O
• Molecular Weight: 317.39
• Mol File: 582333-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-3-(1,8-naphthyridin-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-3-(1,8-naphthyridin-2-yl)-(582333-68-4)
• EPA Substance Registry System: 3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-3-(1,8-naphthyridin-2-yl)-(582333-68-4)

Safety Data

• Hazardous Substances Data: 582333-68-4(Hazardous Substances Data)

Upstream product

• 7521-41-7 2-Aminonicotinaldehyde 
• 63053-27-0 3-(4-Dimethylaminobenzyliden)-2,4-pentandion 

Relevant articles and documents

Synthesis of pyrazoline, pyrimidine and 1,5-benzodiazepine derivatives of 1,8-naphthyridine and evaluation of antibacterial activity

A series of 1-aryl 2,2-bis-(1,8-naphthyridin-2-yl)ethenes 4, 5-aryl-3-methyl-4-(1,8-naphthyridin-2-yl)-1-phenyl-2-pyrazolines 5, 5,6-dihydro-6-aryl-4-methyl-5-(1,8-naphthyridin-2-yl)-2-thioxopyrimidines 6 and 2,3-dihydro-2-aryl-4-methyl-3-(1,8-naphthyridin-2-yl)-1H-1,5-benzodiazepines 7 have been synthesized from 2-aminonicotinaldehyde 1 via α (1,8-naphthyridin-2-yl) banzalacetones 3. The benzalacetones 3 have been readily obtained by the condensation of 1 with 3- arylideneacetylacetones 2. These compounds have been characterized on the basis of elemental analyses, IR, 1H NMR and MS. The compounds 4, 5 and 6 have been screened for their antibacterial activity.