58234-06-3

Basic information

• Product Name: (1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine
• CAS NO: 58234-06-3
• Molecular Formula: C₁₃H₁₁N₃O₂
• Molecular Weight: 241.2453
• Mol File: 58234-06-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 408.4°C at 760 mmHg
• Flash Point: 200.8°C
• Density: 1.25g/cm³
• Vapor Pressure: 7E-07mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: (1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine(58234-06-3)
• EPA Substance Registry System: (1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine(58234-06-3)

Safety Data

• Hazardous Substances Data: 58234-06-3(Hazardous Substances Data)

Usage

Description

(1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine is a hydrazine derivative with the molecular formula C13H10N4O2. It is a yellow solid at room temperature and is commonly used in organic synthesis and research. (1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine features a nitrophenyl and phenyl group connected by a methylidene bridge, and its structure is characterized by a hydrazine functional group.

Uses

Used in Organic Synthesis:
(1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine is used as a building block for the synthesis of more complex organic compounds. Its unique structure allows it to participate in various chemical reactions, making it a valuable component in the creation of new molecules.
Used in Pharmaceutical Research:
(1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine may have potential applications in pharmaceutical research. Its hydrazine functional group and the presence of a nitrophenyl group could make it a candidate for the development of new drugs or drug-like molecules.
Used as an Intermediate in Specialty Chemicals Production:
(1E)-[(4-nitrophenyl)(phenyl)methylidene]hydrazine may also serve as an intermediate in the production of specialty chemicals. Its versatility in chemical reactions and potential reactivity with other compounds make it a useful precursor for the synthesis of specific chemical products.

Upstream product

• 1144-74-7 4-nitrobenzophenone 

Downstream Products

• 1010720-54-3 1-(2,2-difluoro-1-phenylvinyl)-4-nitrobenzene 
• 287192-83-0 6-nitro-3-phenyl-1H-indazole 
• 1431709-20-4 3-(4-nitrophenyl)-1H-indazole 
• 1144-74-7 4-nitrobenzophenone 
• 574747-77-6 1-fluoro-2-(4-nitrophenyl)-2-phenyl-1-trifluoromethylethylene 
• 13271-44-8 -p-dimethylaminophenyl-diphenyl-phosphazin 
• 13271-43-7 -p-anisyl-diphenyl-phosphazin 

Relevant articles and documents

Enantioselective Diarylcarbene Insertion into Si-H Bonds Induced by Electronic Properties of the Carbenes

Catalytic enantioselection usually depends on differences in steric interactions between prochiral substrates and a chiral catalyst. We have discovered a carbene Si-H insertion in which the enantioselectivity depends primarily on the electronic characteristics of the carbene substrate, and the log(er) values are linearly related to Hammett parameters. A new class of chiral tetraphosphate dirhodium catalysts was developed; it shows excellent activity and enantioselectivity for the insertion of diarylcarbenes into the Si-H bond of silanes. Computational and mechanistic studies show how the electronic differences between the two aryls of the carbene lead to differences in energies of the diastereomeric transition states. This study provides a new strategy for asymmetric catalysis exploiting the electronic properties of the substrates.

gem-Difluoroolefination of Diazo Compounds with TMSCF3 or TMSCF2Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors

A new olefination protocol for transition-metal-free cross-coupling of two carbene fragments arising from two different sources, namely, a nonfluorinated carbene fragment resulting from a diazo compound and a difluorocarbene fragment derived from Ruppert-Prakash reagent (TMSCF3) or TMSCF2Br, has been developed. This gem-difluoroolefination proceeds through the direct nucleophilic addition of diazo compounds to difluorocarbene followed by elimination of N2. Compared to previously reported Cu-catalyzed gem-difluoroolefination of diazo compounds with TMSCF3, which possesses a narrow substrate scope due to a demanding requirement on the reactivity of diazo compounds and in-situ-generated CuCF3, this transition-metal-free protocol affords a general and efficient approach to various disubstituted 1,1-difluoroalkenes, including difluoroacrylates, diaryldifluoroolefins, as well as arylalkyldifluoroolefins. In view of the ready availability of diazo compounds and difluorocarbene reagents and versatile transformations of 1,1-difluoroalkenes, this new gem-difluoroolefination method is expected to find wide applications in organic synthesis.