58235-80-6 Usage
Description
METHYL4-BROMOFURAN-2-CARBOXYLATE is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its bromo-furan structure and carboxylate functional group, which contribute to its reactivity and utility in chemical reactions.
Uses
Used in Pharmaceutical Industry:
METHYL4-BROMOFURAN-2-CARBOXYLATE is used as a synthetic intermediate for the preparation of pyrimidinamines and pyridinamines. These compounds act as adenosine receptor modulators, which are important for the treatment of central nervous system (CNS) disorders. The use of METHYL4-BROMOFURAN-2-CARBOXYLATE in this application is due to its ability to facilitate the formation of these biologically active molecules, potentially leading to the development of new therapeutic options for patients suffering from CNS-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 58235-80-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,3 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58235-80:
(7*5)+(6*8)+(5*2)+(4*3)+(3*5)+(2*8)+(1*0)=136
136 % 10 = 6
So 58235-80-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BrO3/c1-9-6(8)5-2-4(7)3-10-5/h2-3H,1H3
58235-80-6Relevant articles and documents
CATALYTIC REDUCTIVE DEBROMINATION - A NEW METHOD FOR THE PREPARATION OF DEUTERO-SUBSTITUTED THIOPHENES AND FURANS
Sharf, V. Z.,Belen'kii, L. I.,Gurovets, A. S.,Karmanova, I. B.
, p. 134 - 138 (2007/10/02)
The principles of the reductive dehalogenation of a number of mono- and dibromo-substituted functional derivatives of thiophene and furan in the presence of a palladium complex applied to silica gel modified with γ-aminopropyl groups were investigated.A one-step method for the preparation of mono- and dideutero-substituted carbonyl compounds of the furan and thiophene series was developed.