5824-40-8

Basic information

• Product Name: Tritylamine
• Synonyms: Benzenemethanamine, alpha,alpha-diphenyl-;Methylamine, 1,1,1-triphenyl-;Triphenylmethanamine;N-TRITYLAMINE;TRIPHENYLMETHYLAMINE;TRIPHENYLAMINOMETHANE;TRITYLAMINE;TRT-NH2
• CAS NO: 5824-40-8
• Molecular Formula: C₁₉H₁₇N
• Molecular Weight: 259.34
• EINECS: 1592732-453-0
• Product Categories: Amines;Building Blocks;C17 to C40+;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 5824-40-8.mol
• Article Data: 21

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 223 °C14 mm Hg(lit.)
• Flash Point: 223°C/14mm
• Appearance: white to light yellow powder
• Density: 0.9242 (rough estimate)
• Vapor Pressure: 1.2E-05mmHg at 25°C
• Refractive Index: 1.7500 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 7.77±0.10(Predicted)
• Water Solubility: Insoluble
• Sensitive: Air Sensitive
• BRN: 2113674
• CAS DataBase Reference: Tritylamine(CAS DataBase Reference)
• NIST Chemistry Reference: Tritylamine(5824-40-8)
• EPA Substance Registry System: Tritylamine(5824-40-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 5824-40-8(Hazardous Substances Data)

Usage

Description

Tritylamine, also known as triphenylmethylamine, is a trityl derivative that is structurally related to Clotrimazole (C587400). It is a white to light yellow powder and is known for its various applications in different industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
Tritylamine is used as a precursor in the preparation of trityl-cysteine analogs, which serve as inhibitors of human mitotic kinesin. This application is crucial in the development of potential treatments for various diseases and conditions related to cell division and mitotic processes.
Used in Fireproofing Industry:
Tritylamine is utilized as a fireproofing agent, providing protection against fire hazards in various settings. Its fire-resistant properties make it a valuable component in the development of fireproofing materials and products.
Used in Organic Synthesis:
Tritylamine is employed in the preparation of diamondoid porous organic salts and N-tritylated β-aminoalcohols, which are useful building blocks in organic synthesis. These compounds are essential in the creation of various chemical products and materials.
General Description:
The reaction of tritylamine with borontrifluoride has been studied, further highlighting its significance in chemical research and development. This information contributes to the understanding of tritylamine's chemical properties and potential applications in various fields.

InChI:InChI=1/C19H17N/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H,20H2/p+1

Upstream product

• 4471-22-1 Phenyl-trityl-amine 
• 631-61-8 ammonium acetate 
• 76-83-5 trityl chloride 
• 64-19-7 acetic acid 
• 5550-96-9 anti-α-(Trityl)-aminoacetophenonoxim 
• 733-90-4 trityllithium 
• 91-20-3 naphthalene 
• 7664-41-7 ammonia 
• 2206-53-3 trityl iodide 
• 7647-01-0 hydrogenchloride 
• 61593-10-0 o-nitrotriphenylmethane 
• 100-47-0 benzonitrile 
• 519-73-3 triphenylmethane 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 

Downstream Products

• 103389-57-7 N,N'-ditrityl-oxalamide 
• 14078-30-9 N,N'-Ditrytylurea 
• 34862-83-4 dichloro-trityl-amine 
• 861530-83-8 bromo-trityl-amine 
• 76-83-5 trityl chloride 
• 102459-48-3 trityl-carbamic acid ethyl ester 
• 14078-04-7 N-tritylbenzamide 
• 20808-83-7 chloro-acetic acid tritylamide 
• 4471-22-1 Phenyl-trityl-amine 
• 20808-90-6 trityl-urea 
• 54150-81-1 N-Tritylthioformamid 
• 137407-85-3 N,N'-ditritylbutane-1,5-pentanediimine 
• 120060-79-9 [3-Methyl-but-(E)-ylidene]-trityl-amine 
• 1726-93-8 N-Triphenylmethyl-trifluoracetamid 

Relevant articles and documents

A new polymorph of triphenyl-methyl-amine: The effect of hydrogen bonding

Crystallization of the hexane reaction mixture after treatment of LiGe(OCH2CH2NMe2)3 with PH3CN 3 gives rise to a new triclinic (space group P ) polymorph of triphenyl-methyl-amine, Cl9H17N, (I), cont

Synthetic method of 3-hydroxyazetidine hydrochloride

The invention discloses a synthetic method of 3-hydroxyazetidine hydrochloride, and belongs to the field of pharmacy. The synthetic method of the 3-hydroxyazetidine hydrochloride comprises the following steps: introducing hydrogen chloride gas into a solution formed by N-(triphenylmethyl)-3-hydroxyazetidine and a first organic solvent to carry out a reaction of removing triphenylchloromethane, andcarrying out solid-liquid separation to obtain the 3-hydroxyazetidine hydrochloride. The period for preparing the 3-hydroxyazetidine hydrochloride by utilizing the synthesis method is short, the safety is good, the use of toxic or expensive reagents is avoided, the reaction yield is high, the 3-hydroxyazetidine hydrochloride with high quality purity can be obtained, the operation is simple and convenient, and the method is suitable for large-scale industrial production.

Isoselective Lactide Ring Opening Polymerisation using [2]Rotaxane Catalysts

Polylactide (PLA) is a fully biodegradable and recyclable plastic, produced from a bio-derived monomer: it is a circular economy plastic. Its properties depend upon its stereochemistry and isotactic PLA shows superior thermal-mechanical performances. Here, a new means to control tacticity by exploiting rotaxane conformational dynamism is described. Dynamic achiral [2]rotaxanes can show high isoselectivity (Pi=0.8, 298 K) without requiring any chiral additives and enchain by a chain end control mechanism. The organocatalytic dynamic stereoselectivity is likely applicable to other small-molecule and polymerization catalyses.