58306-67-5

Basic information

• Product Name: N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide
• Synonyms: N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide;Einecs 261-206-6;Fenbendazole F-2 compound
• CAS NO: 58306-67-5
• Molecular Formula: C₁₅H₁₆N₂O₂S
• Molecular Weight: 288.36474
• EINECS: 261-206-6
• Mol File: 58306-67-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 525.4°Cat760mmHg
• Flash Point: 271.6°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 3.93E-11mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide(58306-67-5)
• EPA Substance Registry System: N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide(58306-67-5)

Safety Data

• Hazardous Substances Data: 58306-67-5(Hazardous Substances Data)

Usage

General Description

N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide is a chemical compound that contains an amino group and a methoxyacetamide group. It also has a phenylthio moiety, which is a sulfide with a phenyl group attached. N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide may have potential use in the field of medicinal chemistry due to its structure and potential biological activity. It could also be used as a building block for the synthesis of other organic compounds. Understanding the properties and reactions of this compound can provide insights into its potential applications in various fields of science and technology.

InChI:InChI=1/C15H16N2O2S/c1-19-10-15(18)17-14-9-12(7-8-13(14)16)20-11-5-3-2-4-6-11/h2-9H,10,16H2,1H3,(H,17,18)

Upstream product

• 63470-85-9 2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide 
• 108-90-7 chlorobenzene 
• 43156-47-4 2-nitro-5-phenylthioaniline 
• 108-86-1 bromobenzene 

Downstream Products

• 73851-07-7 C₂₀H₂₂N₄O₇S 
• 58306-33-5 C₂₁H₂₄N₄O₆S 
• 58306-30-2 Febantel 

Relevant articles and documents

Preparation method of 2-amino-5-phenylthio-(2-methoxy)acetanilide

The invention belongs to the technical field of organic synthesis and particularly relates to a preparation method of 2-amino-5-phenylthio-(2-methoxy)acetanilide. According to the method, 2-nitro-5-(phenylthio)aniline is prepared from 2-nitro-5-mercaptoaniline and benzene halide and then subjected to a reaction with methyl methoxyacetate, 2-nitro-5-phenylthio-(2-methoxy)acetanilide is generated and subjected to catalytic hydrogenation reduction finally, and the target product is obtained. The preparation method has good reaction selectivity, and the obtained target product is high in purity and yield; use of high-toxicity materials is avoided, requirements for equipment and operation conditions are reduced, and safety and stability of the preparation method are improved; doses of the reaction materials are optimized, and excess benzene halide and methyl methoxyacetate can be recycled after being recovered simply; little solid waste is produced, waste treatment cost is reduced greatly,and the requirement for environmental protection is met.

Substituted phenylisothioureas and processes for their preparation and use

N-[2-(Substituted amido)phenyl]-N'-carbonyl-S-substituted isothioureas bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(substituted amido)-phenyl group are anthelmintic agents. The compounds, of which N-(2-acetamido-4-phenoxyphenyl)-N'-carbomethoxy-S-methylthiourea is a typical example, are prepared through the reaction of S-substituted N-(mercaptohalomethylene)carbamic acid ester and an apropriately substituted 2-aminoanilide, or through alkylation of the corresponding S-unsubstituted thiourea.