5837-39-8

Basic information

• Product Name: 3β-Methoxy-5α-cholestan-6-one
• Synonyms: 3β-Methoxy-5α-cholestan-6-one
• CAS NO: 5837-39-8
• Molecular Formula: C₂₈H₄₈O₂
• Molecular Weight: 416.67952
• Mol File: 5837-39-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3β-Methoxy-5α-cholestan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-Methoxy-5α-cholestan-6-one(5837-39-8)
• EPA Substance Registry System: 3β-Methoxy-5α-cholestan-6-one(5837-39-8)

Safety Data

• Hazardous Substances Data: 5837-39-8(Hazardous Substances Data)

Upstream product

• 127460-91-7 (3S,8S,9S,10R,13R,14S,17R)-3-methoxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-6-nitro-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene 
• 1174-92-1 cholesteryl methyl ether 
• 70223-10-8 6-ketocholestanol 
• 149-73-5 trimethyl orthoformate 
• 74-88-4 methyl iodide 
• 85198-21-6 3β-methoxy-4-cholesten-6α-ol 
• 85249-15-6 6α-hydroxy-3β-methoxy-5α-cholestane 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 116329-75-0 3β-methoxy-6β-(3'-benzoylphenyl)acetamidocholestane 
• 116329-76-1 C₄₃H₆₁NO₃ 
• 103721-15-9 Toluene-4-sulfonic acid 2-[(3S,5S,6R,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-3-methoxy-6,10,13-trimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yloxy]-ethyl ester 

Relevant articles and documents

Recation of Nitro-alkenes with Iodotrimethylsilane: A New Method for the Conversion of Vinyl Nitrosteroids to Ketosteroids

Iodotrimethylsilane generated in situ from chlorotrimethylsilane and sodium iodide effects the reduction of nitro-alkenes (1a-e) and (5) at -5 to O deg C to furnish the ketones (2a-e) and (6) respectively as the major products.

Preparation and Cleavage Reactions of Some Steroidal Epoxides

The steroidal epoxides (12), (13), (28), and (34) have been prepared and their reactions investigated.Attempts to prepare the epoxides (12) and (13) by the action of dimethylsulphonium methyilde or dimethylsulphoxonium methylide on the ketone 1 gave instead the rearranged product (2) and its methyl ether (3).Compound (2) has also been obtained by base-catalysed isomerization of the spiro-epoxide (13).Lewis acid-catalysed rearrangement of epoxides (12), (28), and (34) into the A-homo-B-norsteroids (16), (29), and (43) respectively is described.