583878-45-9

Basic information

• Product Name: tert-butyl 4-{[5-formyl-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate
• Synonyms: tert-butyl 4-{[5-formyl-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate
• CAS NO: 583878-45-9
• Molecular Weight: 359.449
• Mol File: 583878-45-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-{[5-formyl-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-{[5-formyl-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate(583878-45-9)
• EPA Substance Registry System: tert-butyl 4-{[5-formyl-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate(583878-45-9)

Safety Data

• Hazardous Substances Data: 583878-45-9(Hazardous Substances Data)

Upstream product

• 344361-90-6 5-ethoxycarbonyl-6-methyl-2-methylsulfanylpyrimidin-4(3H)-one 
• 583878-42-6 ethyl 4-chloro-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 583878-44-8 tert-butyl 4-{[5-(hydroxymethyl)-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate 
• 583878-43-7 ethyl 4-[4-(tert-butoxycarbonyl)anilino]-6-methyl-2-(methylsulfanyl)-5-pyrimidinecarboxylate 
• 18144-47-3 tert-butyl 4-aminobenzoate 
• 1462-12-0 diethyl ethylidenemalonate 

Downstream Products

• 583873-84-1 tert-butyl 4-(4-methyl-7-oxo-2-(4-phenyl-1-piperazinyl)pyrido[2,3-d]pyrimidin-8(7H)-yl)benzoate 
• 583873-90-9 4-(4-methyl-7-oxo-2-(4-phenyl-1-piperazinyl)pyrido[2,3-d]pyrimidin-8(7H)-yl)benzoic acid 
• 583878-47-1 4-(4-methyl-7-oxo-2-(4-phenyl-1-piperazinyl)pyrido[2,3-d]pyrimidin-8(7H)-yl)benzoyl chloride 
• 583873-82-9 tert-butyl 4-(4-methyl-2-(methylsulfonyl)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)benzoate 
• 583873-81-8 tert-butyl 4-(4-methyl-2-(methylsulfanyl)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)benzoate 
• 583878-52-8 4-(4-methyl-2-(methylsulfanyl)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)benzoyl chloride 
• 583878-40-4 4-(4-methyl-2-(methylsulfanyl)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)benzoic acid 
• 642455-54-7 tert-butyl 4-{[5-[(1E)-3-ethoxy-3-oxo-1-propenyl]-6-methyl-2-(methylsulfanyl)-4-pyrimidinyl]amino}benzoate 

Relevant articles and documents

Solid-phase synthesis of pyrido[2,3-d]pyrimidin-7-ones

A novel solid-phase method for the synthesis of 4-methyl-pyrido[2,3-d] pyrimidin-7-one compounds with two diversity points is described. The polymer supported methylsulfonyl derivatives A3, achieved by coupling compound G with different resin-bound amines A1 followed by oxidation with MCPBA, are substituted with several amines R1R2NH. Final cleavage affords 126 compounds having formula H in good yield and purity.