58416-04-9 Usage
Description
3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester, also known as Dimethyl 3,4-dihydroxythiophene-2,5-dicarboxylate, is a white powder chemical compound derived from the thiophene ring system. It is characterized by its reactive functional groups, which make it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester is used as a key reactant for the synthesis of various bioactive compounds, particularly in the pharmaceutical industry. Its ability to undergo Curtius-like rearrangement reactions allows for the creation of 2,5-diamide-substituted five-membered heterocycles based on the thiophene, pyrrole, and furan ring systems, which are essential in the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester serves as an important intermediate for the production of various organic compounds. Its unique structure and reactivity make it a valuable building block for the synthesis of complex molecules, including those with potential applications in materials science, agrochemicals, and other specialty chemicals.
Used in Research and Development:
3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester is also utilized in research and development laboratories for the exploration of novel chemical reactions and the development of new synthetic methodologies. Its versatility in undergoing various chemical transformations makes it a valuable tool for chemists working on the design and synthesis of new molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 58416-04-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,4,1 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58416-04:
(7*5)+(6*8)+(5*4)+(4*1)+(3*6)+(2*0)+(1*4)=129
129 % 10 = 9
So 58416-04-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O6S/c1-13-7(11)5-3(9)4(10)6(15-5)8(12)14-2/h9-10H,1-2H3
58416-04-9Relevant articles and documents
2,5-Diamide-Substituted Five-Membered Heterocycles: Challenging Molecular Synthons
Fabbro, Chiara,Armani, Simone,Carloni, Laure-Elie,De Leo, Federica,Wouters, Johan,Bonifazi, Davide
, p. 5487 - 5500 (2014/10/15)
We describe synthetic routes for preparing previously unknown 2,5-diamide-substituted five-membered heterocycles based on the thiophene, pyrrole, and furan ring systems by exploiting Curtius-like rearrangement reactions. Conformation analysis of the 2,5-diamidothiophene derivatives identified a "closed" conformation, in which the two carbonyl O atoms are in close contact with the thiophene S atom.
