58486-00-3

Basic information

• Product Name: 1-BENZYLPYRROLIDINE-2,3-DIONE
• Synonyms: 1-BENZYLPYRROLIDINE-2,3-DIONE
• CAS NO: 58486-00-3
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21054
• EINECS: -0
• Mol File: 58486-00-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BENZYLPYRROLIDINE-2,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYLPYRROLIDINE-2,3-DIONE(58486-00-3)
• EPA Substance Registry System: 1-BENZYLPYRROLIDINE-2,3-DIONE(58486-00-3)

Safety Data

• Hazardous Substances Data: 58486-00-3(Hazardous Substances Data)

Usage

Type

Chemical compound

Derivative

Pyrrolidone

Usage

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Molecular Weight

203.24 g/mol

Physical State

White to off-white solid

Solubility

Insoluble in water, soluble in organic solvents

Application

Versatile building block in organic synthesis

Production

Used in the production of various pharmaceuticals, agrochemicals, and other fine chemicals

Safety

Handle with care and follow proper safety protocols

Upstream product

• 97391-36-1 1-benzyl-3-<(N,N-dimethylamino)methylene>-2-pyrrolidinone 
• 100-46-9 benzylamine 
• 261967-37-7 1-benzyl-3,3-bis-methylsulfanyl-pyrrolidin-2-one 
• 100-39-0 benzyl bromide 
• 106180-86-3 1-Benzyl-3,3-dimethoxypyrrolidin-2-one 
• 96124-43-5 methyl 1-benzyl-3-hydroxy-3-pyrrolin-2-one-4-carboxylate 
• 5336-50-5 1-benzyl-4,5-dioxopyrrolidine-3-carboxylic acid ethyl ester 

Downstream Products

• 101878-81-3 1-benzyl-pyrrolidine-2,3-dione-3-phenylhydrazone 
• 5336-34-5 3-hydroxy-1-benzyl-2-pyrrolidinone 
• 58485-96-4 2-benzyl-4-phenyl-1,4-dihydropyrrolo[3,4-b]indol-3-(2H)-one 
• 1394297-98-3 C₃₀H₂₅Cl₂N₃O 

Relevant articles and documents

Synthesis of new pyrrolo[3,4-b]indol-3-ones as latent substrates for pyrrolo[3,4-b]indoles

We report the synthesis of new examples of the 1,4-dihydropyrrolo[3,4-b]indol-3(2H)-one ring system via Fischer indolization between the appropriate phenylhydrazines and pyrrolidine-2,3-diones. Lithiation at the C-1 position with lithium diisopropylamide following by quenching with iodomethane affords 1-methyl-1,4-dihydropyrrolo[3,4-b]indol-3(2H)-ones in excellent yield.

Reaction of Singlet Oxygen with Enamino Carbonyl Systems. A General Method for the Synthesis of α-Keto Derivatives of Lactones, Esters, Amides, Lactams, and Ketones

A general method for the introduction of a ketone α to the carbonyl group of a ketone, lactone. ester, substituted amide, or lactam has been developed involving the formation and dye-sensitized photooxygenation of enamino carbonyl intermediates.