58567-05-8 Usage
Description
DIETHYL 2-HYDROXY-2-METHYLMALONATE, also known as Diethyl Methyltartronate, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals and chemicals. It is characterized by its chemical structure, which includes a hydroxyl group and a methyl group attached to a malonate backbone, making it a versatile building block in the chemical industry.
Uses
Used in Pharmaceutical Industry:
DIETHYL 2-HYDROXY-2-METHYLMALONATE is used as an intermediate in the synthesis of (R)-(-)-chlozolinate, an important antifungal agent. This application is significant because it helps in the development of new antifungal medications to combat fungal infections, which can be life-threatening in some cases.
Additionally, as an intermediate, DIETHYL 2-HYDROXY-2-METHYLMALONATE may also be used in the synthesis of other pharmaceutical compounds, contributing to the development of a wide range of medications for various medical conditions.
Used in Chemical Industry:
DIETHYL 2-HYDROXY-2-METHYLMALONATE is used as a building block for the synthesis of various chemicals and materials. Its unique chemical structure allows it to be a valuable component in the creation of new compounds with specific properties, such as improved stability, reactivity, or bioavailability. This versatility makes it an essential compound in the chemical industry for the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 58567-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,6 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58567-05:
(7*5)+(6*8)+(5*5)+(4*6)+(3*7)+(2*0)+(1*5)=158
158 % 10 = 8
So 58567-05-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H14O5/c1-3-12-7(10)6(5-9)8(11)13-4-2/h6,9H,3-5H2,1-2H3
58567-05-8Relevant articles and documents
Highly efficient C-H hydroxylation of carbonyl compounds with oxygen under mild conditions
Liang, Yu-Feng,Jiao, Ning
supporting information, p. 548 - 552 (2014/01/23)
A transition-metal-free Cs2CO3-catalyzed α-hydroxylation of carbonyl compounds with O2 as the oxygen source is described. This reaction provides an efficient approach to tertiary α-hydroxycarbonyl compounds, which are highly valued chemicals and widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very environmentally friendly and practical. This transformation is highly efficient and highly selective for tertiary C(sp3)-H bond cleavage. OH, so simple! A transition-metal-free Cs2CO 3-catalyzed α-hydroxylation of carbonyl compounds with O 2 provided a variety of tertiary α-hydroxycarbonyl compounds (see scheme; DMSO=dimethyl sulfoxide), which are widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very efficient and practical.
Nickel-catalyzed hydroxylation of 1,3-dicarbonyl compounds by dimethyldioxirane
Adam, Waldemar,Smerz, Alexander K.
, p. 5799 - 5804 (2007/10/03)
Various 1,3-dicarbonyl compounds were directly hydroxylated by dimethyldioxirane, a preparative useful extension of this oxidation is the efficient catalysis by Ni(II) salts through chelation.
Process for preparing alkyl esters of C-alkyl-tartronic or C-halogenalkyl-tartronic acids
-
, (2008/06/13)
A process is herein described for obtaining lower alkyl esters of C-alkyl-tartronic or C-halogenalkyl-tartronic acids according to the reaction: STR1 in which R and R2, like or unlike each other, may be alkyls having C1 -C5 or halogenalkyls having C1 -C5 and R1 is an alkyl having C1 -C5.
