586413-59-4Relevant articles and documents
Total synthesis of anti-HIV agent chloropeptin I
Deng, Hongbo,Jung, Jae-Kyung,Liu, Tao,Kuntz, Kevin W.,Snapper, Marc L.,Hoveyda, Amir H.
, p. 9032 - 9034 (2007/10/03)
A convergent diastereo- and enantioselective total synthesis of anti-HIV agent chloropeptin I is reported. Important features of the total synthesis include: (1) the use of Ti-catalyzed cyanide addition to imines to prepare a requisite amino acid moiety,