586960-71-6

Basic information

• Product Name: Piperazine, 1-benzoyl-4-(2-propenyl)-
• CAS NO: 586960-71-6
• Molecular Formula: C14H18N2O
• Molecular Weight: 230.31
• Mol File: 586960-71-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-benzoyl-4-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-benzoyl-4-(2-propenyl)-(586960-71-6)
• EPA Substance Registry System: Piperazine, 1-benzoyl-4-(2-propenyl)-(586960-71-6)

Safety Data

• Hazardous Substances Data: 586960-71-6(Hazardous Substances Data)

Upstream product

• 13754-38-6 N-Benzoylpiperazine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 13961-36-9 1-allylpiperazine 

Relevant articles and documents

Unique spirocyclopiperazinium salt I: Synthesis and structure-activity relationship of spirocyclopiperazinium salts as analgesics

Based on the structure of compound 3, two series of spirocyclopiperazinium derivatives 7a-n and 10a-h were synthesized and evaluated for their in vivo analgesic and sedative activities. Compounds 7f and 10c were discovered to exhibit excellent analgesic activity. Structure-activity relationships revealed that anion of the quaternary salt affected the analgesic and sedative activity significantly; the allyl group is a most effective group among the compounds 7a-n; the electron-released substitute on the aromatic ring is favorable to increase the analgesic activity.