58743-80-9

Basic information

• Product Name: 1-(4-Bromophenyl)-4-ethoxybenzene
• Synonyms: 1-(4-Bromophenyl)-4-ethoxybenzene;4-Bromo-4'-ethoxybiphenyl
• CAS NO: 58743-80-9
• Molecular Formula: C₁₄H₁₃BrO
• Molecular Weight: 277.15642
• Mol File: 58743-80-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Bromophenyl)-4-ethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Bromophenyl)-4-ethoxybenzene(58743-80-9)
• EPA Substance Registry System: 1-(4-Bromophenyl)-4-ethoxybenzene(58743-80-9)

Safety Data

• Hazardous Substances Data: 58743-80-9(Hazardous Substances Data)

Usage

Description

1-(4-Bromophenyl)-4-ethoxybenzene is a chemical compound characterized by the molecular formula C14H13BrO. It is a derivative of benzene, featuring a bromine atom and an ethoxy group attached to the phenyl ring. This white to off-white solid has a molecular weight of 259.16 g/mol and is widely utilized as a fundamental building block in organic synthesis.

Uses

Used in Pharmaceutical Industry:
1-(4-Bromophenyl)-4-ethoxybenzene is used as an intermediate in the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its ability to be modified and incorporated into more complex molecules makes it a valuable component in drug development.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-Bromophenyl)-4-ethoxybenzene is used as a precursor for the development of new agrochemicals. Its structural properties allow for the creation of compounds that can be applied in pest control and crop protection.
Used in Material Science:
1-(4-Bromophenyl)-4-ethoxybenzene is also utilized in material science for the production of specific materials with desired properties. Its versatility in organic synthesis enables the creation of materials with tailored characteristics for various applications.
Safety Note:
Given the potential reactivity and toxicity of 1-(4-Bromophenyl)-4-ethoxybenzene, it is crucial to adhere to proper handling and storage procedures when working with this compound to ensure safety in research and industrial settings.

Upstream product

• 74-96-4 ethyl bromide 
• 29558-77-8 4-bromo-4'-hydroxybiphenyl 
• 589-87-7 1,4-bromoiodobenzene 
• 22237-13-4 (4-ethoxyphenyl)boronic acid 
• 75-03-6 ethyl iodide 
• 584-08-7 potassium carbonate 
• 64-67-5 diethyl sulfate 

Downstream Products

• 1192136-38-1 (S)-((3aS,5S,6R,6aS)-6-(tert-butyldimethylsilyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(4'-ethoxybiphenyl-4-yl)methanol 
• 182344-29-2 4'-ethoxybiphenyl-4-yl boronic acid 
• 58743-78-5 4'-ethoxybiphenyl-4-carbonitrile 

Relevant articles and documents

C-Aryl glucoside SGLT2 inhibitors containing a biphenyl motif as potential anti-diabetic agents

A series of highly active C-aryl glucoside SGLT2 inhibitors containing a biphenyl motif were designed and synthesized for biological evaluation. Among the compounds tested, compound 16l demonstrated high inhibitory activity against SGLT2 (IC50 = 1.9 nM) with an excellent pharmacokinetic profile. Further study indicated that the in vivo efficacy of compound 16l was comparable to that of dapagliflozin, suggesting that further development would be worthwhile.

SUBSTITUTED CYCLOALKANECARBOXYLIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS

Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula STR1 wherein each T is a substituent g roup; x is 0, 1, or 2; the group D represents STR2 the subscript "e" is 2 or 3; the group R 14 represents a variety of possible substituent groups of the cycloalkyl ring between D and G; the subscript "k" is 0-2; and the group G represents M, STR3 in which M represents--CO 2 H,--CON(R 11) 2, or--CO 2 R 12 ; and R 13 represents any of the side chains of the 19 noncyclic occurring amino acids. "