588-22-7

Basic information

• Product Name: 3,4-D
• Synonyms: (3,4-dichlorophenoxy)-aceticaci;3,4-da;LABOTEST-BB LT00233086;3,4-DICHLOROPHENOXYACETIC ACID;3,4-D;3,4-d (iso);3,4-D solution;3,4-Dichlorophenoxyacetic acid solution
• CAS NO: 588-22-7
• Molecular Formula: C₈H₆Cl₂O₃
• Molecular Weight: 221.04
• EINECS: 209-612-4
• Product Categories: C8;Carbonyl Compounds;Carboxylic Acids
• Mol File: 588-22-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 138-140 °C(lit.)
• Boiling Point: 316.96°C (rough estimate)
• Flash Point: 2 °C
• Appearance: White/Crystalline Powder
• Density: 1.4564 (rough estimate)
• Vapor Pressure: 1.53E-05mmHg at 25°C
• Refractive Index: 1.5000 (estimate)
• Storage Temp.: APPROX 4°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 2.99±0.10(Predicted)
• Water Solubility: 457.6mg/L(25 oC)
• CAS DataBase Reference: 3,4-D(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-D(588-22-7)
• EPA Substance Registry System: 3,4-D(588-22-7)

Safety Data

• Hazard Codes: Xi,Xn,F
• Statements: 36/37/38-36-20/21/22-11
• Safety Statements: 26-37/39-36-16
• RIDADR: 2811
• WGK Germany: 3
• RTECS: AG6830000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 588-22-7(Hazardous Substances Data)

Usage

Description

3,4-Dichlorophenoxyacetic acid, commonly known as 3,4-D, is a phenoxyacetic herbicide characterized by the replacement of hydrogens at positions 3 and 4 of the phenyl group with chlorines. It is a chlorophenoxyacetic acid derivative with potent herbicidal properties, making it a valuable compound in various applications.

Uses

Used in Chemical Synthesis:
3,4-D is used as a key component in the synthesis of layered organic-inorganic nanohybrid materials, such as zinc-aluminum-3,4-dichlorophenoxyacetate. This application takes advantage of its chemical properties to create innovative materials with potential uses in various industries.
Used in Agriculture:
In the agricultural industry, 3,4-D is used as a herbicide for controlling the growth of broadleaf plants and weeds. Its effectiveness in targeting specific plant species without harming crops makes it a valuable tool for farmers and growers, helping to increase crop yields and maintain the quality of agricultural products.
Used in Environmental Management:
3,4-D is also utilized in environmental management for the control of invasive plant species that can disrupt ecosystems and negatively impact native flora and fauna. By selectively targeting these invasive plants, 3,4-D helps to preserve the balance of natural habitats and protect biodiversity.
Used in Research and Development:
In the field of research and development, 3,4-D serves as a starting material for the creation of new compounds and formulations with improved herbicidal properties. Scientists and chemists use it to develop more effective and environmentally friendly herbicides, contributing to the ongoing efforts to create sustainable agricultural practices.

InChI:InChI=1/C8H6Cl2O3/c9-6-2-1-5(3-7(6)10)13-4-8(11)12/h1-3H,4H2,(H,11,12)

Upstream product

• 39975-26-3 sodium 3,4-dichlorophenoxide 
• 105-36-2 ethyl bromoacetate 
• 95-77-2 3,4-dichlorophenol 
• 32026-08-7 2-(3,4-dichlorophenoxy)acetamide 
• 62855-72-5 ethyl 2-(3,4-dichlorophenoxy)acetate 

Downstream Products

• 62855-72-5 ethyl 2-(3,4-dichlorophenoxy)acetate 
• 52696-40-9 (3,4-Dichloro-phenoxy)-acetic acid 1-(3-chloro-4-trifluoromethyl-phenyl)-3,3-dimethyl-ureidomethyl ester 
• 15422-26-1 N-(4-Chloro-phenyl)-2-(3,4-dichloro-phenoxy)-acetamide 
• 15422-28-3 N-(3-Chloro-benzyl)-2-(3,4-dichloro-phenoxy)-acetamide 
• 122-59-8 2-phenoxyacetic acid 
• 98919-01-8 (3,4-Dichloro-phenoxy)-acetic acid allyl ester 
• 128103-37-7 1-[(3,4-Dichlorophenoxy)acetyl]-2-(1-pyrrolidinylmethyl)piperidine fumarate 
• 1052694-81-1 5-((3,4-dichlorophenoxy)methyl)-1,3,4-thiadiazol-2-amine 

Relevant articles and documents

NURR1 RECEPTOR MODULATORS

Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.

An Efficient One-Pot Synthesis of 2-(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) is an important target for new bleaching herbicides discovery. As a continuous work to discover novel crop selective HPPD inhibitor, a series of 2-(aryloxyacetyl)cyclohexane-1,3-diones were rationally designed and synthesized by an efficient one-pot procedure using N,N′-carbonyldiimidazole (CDI), triethylamine, and acetone cyanohydrin in CH2Cl2. A total of 58 triketone compounds were synthesized in good to excellent yields. Some of the triketones displayed potent in vitro Arabidopsis thaliana HPPD (AtHPPD) inhibitory activity. 2-(2-((1-Bromonaphthalen-2-yl)oxy)acetyl)-3-hydroxycyclohex-2-en-1-one, II-13, displayed high, broad-spectrum, and postemergent herbicidal activity at the dosage of 37.5-150 g ai/ha, nearly as potent as mesotrione against some weeds. Furthermore, II-13 showed good crop safety against maize and canola at the rate of 150 g ai/ha, indicating that II-13 might have potential as a herbicide for weed control in maize and canola fields. II-13 is the first HPPD inhibitor showing good crop safety toward canola.

THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE

The present invention relates to substituted thiadiazole compounds of the formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.