58844-73-8

Basic information

• Product Name: o-(Phenylsulfonyl)benzoic acid
• Synonyms: o-(Phenylsulfonyl)benzoic acid
• CAS NO: 58844-73-8
• Molecular Formula: C₁₃H₁₀O₄S
• Molecular Weight: 262.2811
• Mol File: 58844-73-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 143-144 °C
• Boiling Point: 490.8°Cat760mmHg
• Flash Point: 250.6°C
• Appearance: /
• Density: 1.378g/cm³
• Vapor Pressure: 1.9E-10mmHg at 25°C
• Refractive Index: 1.616
• PKA: 2.83±0.36(Predicted)
• CAS DataBase Reference: o-(Phenylsulfonyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: o-(Phenylsulfonyl)benzoic acid(58844-73-8)
• EPA Substance Registry System: o-(Phenylsulfonyl)benzoic acid(58844-73-8)

Safety Data

• Hazardous Substances Data: 58844-73-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H10O4S/c14-13(15)11-8-4-5-9-12(11)18(16,17)10-6-2-1-3-7-10/h1-9H,(H,14,15)

Upstream product

• 109-72-8 n-butyllithium 
• 60-29-7 diethyl ether 
• 127-63-9 diphenyl sulphone 
• 15719-64-9 methylammonium carbonate 
• 5324-79-8 1-bromo-2-(phenylsulfonyl)benzene 
• 13963-35-4 2-(phenylthio)toluene 
• 7018-84-0 phenyl o-tolyl sulfone 
• 1527-12-4 2-(phenylthio)benzoic acid 
• 618-41-7 Benzenesulfinic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 7732-18-5 water 
• 71-41-0 pentan-1-ol 
• 17333-74-3 2-methylbenzene diazonium 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 80404-63-3 2-benzenesulfonyl-benzoic acid ethyl ester 
• 67373-14-2 methyl 2-(phenylsulfonyl)benzoate 
• 66728-54-9 2-benzenesulfonyl-benzoic acid amide 
• 201216-01-5 phenyl(2-(phenylsulfonyl)phenyl)methanone 

Relevant articles and documents

Copper(II)-catalyzed direct sulfonylation of C(sp2)-H bonds with sodium sulfinates

A copper-catalyzed direct sulfonylation of C(sp2)-H bonds with sodium sulfinates using a removable directing group is described. This reaction tolerates a wide range of functional groups, providing an efficient protocol for the synthesis of diverse aryl sulfones. Moreover, a series of 2,6-disubstituted benzamides could be synthesized via sequential C-H functionalization.

Aromatic pyrrolidine amide prolyl endopeptidase inhibitors

A series of aromatic pyrrolidine derivatives and suitable pharmaceutically acceptable salts thereof are disclosed. These compounds are useful as PEP inhibitors in the treatment of Alzheimer's disease, amnesia, dementia, anxiety ischemia, or stroke.