58856-73-8

Basic information

• Product Name: OMEGA-AMINOHEXYL-AGAROSE
• Synonyms: OMEGA-AMINOHEXYL-AGAROSE;aminohexyl-sepharose;6-AMINOHEXYL-AGAROSE 4B FOR AFFINITY CHR OMATOGRAPHY;omega-Aminopentylagarose4B,6B;quality:biochemica;omega-Aminohexylagarose4B,6B;omega-Aminobutylagarose4B,6B;quality:biochemica,foraffinitychromatographyactivatedwithcyanogenbromide
• CAS NO: 58856-73-8
• Molecular Weight: 0
• EINECS: 231-791-2
• Mol File: 58856-73-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /saline suspension
• Density: 1.026 g/mL at 20 °C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: OMEGA-AMINOHEXYL-AGAROSE(CAS DataBase Reference)
• NIST Chemistry Reference: OMEGA-AMINOHEXYL-AGAROSE(58856-73-8)
• EPA Substance Registry System: OMEGA-AMINOHEXYL-AGAROSE(58856-73-8)

Safety Data

• F: 10-34
• Hazardous Substances Data: 58856-73-8(Hazardous Substances Data)

Usage

Description

OMEGA-AMINOHEXYL-AGAROSE is a type of agarose resin that is functionalized with omega-aminohexyl groups. It is commonly used in various biotechnological and pharmaceutical applications due to its unique properties, such as its ability to bind and separate specific molecules through affinity chromatography.

Uses

Used in Biotechnology Industry:
OMEGA-AMINOHEXYL-AGAROSE is used as a chromatography medium for the purification and separation of biomolecules, such as proteins, peptides, and nucleic acids. Its omega-aminohexyl groups provide a stable and versatile platform for the covalent attachment of various ligands, enabling selective binding and separation of target molecules.
Used in Pharmaceutical Industry:
OMEGA-AMINOHEXYL-AGAROSE is used as a support matrix for the development of affinity chromatography systems, which are essential in the isolation and purification of therapeutic proteins, antibodies, and other bioactive molecules. This application is crucial for the production of high-quality and pure pharmaceutical products.
Used in Research and Development:
OMEGA-AMINOHEXYL-AGAROSE is used as a research tool for the study of molecular interactions, protein expression, and the development of novel biotechnological applications. Its ability to bind specific molecules makes it a valuable tool for investigating molecular mechanisms and designing new therapeutic strategies.
Specific Application:
OMEGA-AMINOHEXYL-AGAROSE has been used for the coupling of serotype b-specific carbohydrate antigen (SbAg) of Actinobacillus actinomycetemcomitans Y4 for the isolation of anti-SbAg antibodies using protein chromatography. This application demonstrates the resin's utility in the development of specific affinity chromatography systems for the purification of antibodies and other biomolecules.

Biochem/physiol Actions

ω-aminoalkyl-agaroses are used in chromatography. In these, the protein is retained by lipophilic association between the hydrocarbon side chains on the agarose and hydrophobic pockets in the protein.