588715-60-0 Usage
General Description
3-[(3,4-DICHLOROBENZYL)OXY]BENZALDEHYDE is a chemical compound with the molecular formula C14H10Cl2O2. It is a benzaldehyde derivative with the addition of a 3,4-dichlorobenzyl oxy group. 3-[(3,4-DICHLOROBENZYL)OXY]BENZALDEHYDE is commonly used in organic synthesis and pharmaceutical research as an intermediate in the production of various substances. Its properties and reactivity make it suitable for use in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 3-[(3,4-DICHLOROBENZYL)OXY]BENZALDEHYDE is important in the field of organic chemistry due to its potential for creating new molecules with interesting properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 588715-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,8,7,1 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 588715-60:
(8*5)+(7*8)+(6*8)+(5*7)+(4*1)+(3*5)+(2*6)+(1*0)=210
210 % 10 = 0
So 588715-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H10Cl2O2/c15-13-5-4-11(7-14(13)16)9-18-12-3-1-2-10(6-12)8-17/h1-8H,9H2
588715-60-0Relevant articles and documents
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558
Takano, Rieko,Yoshida, Masao,Inoue, Masahiro,Honda, Takeshi,Nakashima, Ryutaro,Matsumoto, Koji,Yano, Tatsuya,Ogata, Tsuneaki,Watanabe, Nobuaki,Hirouchi, Masakazu,Kimura, Takako,Toda, Narihiro
supporting information, p. 5546 - 5565 (2015/11/11)
GPR40 agonists stimulate insulin secretion only under the presence of high glucose concentration. Based on this mechanism, GPR40 agonists are believed to be promising novel insulin secretagogues with low risk of hypoglycemia. The optimizations of 3-aryl-3-ethoxypropanoic acids were performed to improve in vitro activity. We discovered compound 29r (DS-1558), (3S)-3-ethoxy-3-(4-{[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy}phenyl)propanoic acid, which was confirmed to have an enhancing effect on glucose-dependent insulin secretion after intravenous glucose injection in SD rats.
