58981-35-4

Basic information

• Product Name: 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE
• Synonyms: 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE;RARECHEM AN KA 1403;2-(4-METHYL-1,3-THIAZOL-5-YL)ETHANAMINE;4-METHYL-5-THIAZOLEETHANAMINE;2-(4-Methylthiazol-5-yl)ethylamine oxalic acid;2-(4-methylthiazol-5-yl)ethanamine;2-(4-methyl-1,3-thiazol-5-yl)ethanamine(SALTDATA: 2HBr);[2-(4-Methyl-1,3-thiazol-5-yl)ethyl]amine dihydrochloride
• CAS NO: 58981-35-4
• Molecular Formula: C₆H₁₀N₂S
• Molecular Weight: 142.22
• Product Categories: Building Blocks;Thiazole
• Mol File: 58981-35-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 244.8 °C at 760 mmHg
• Flash Point: 101.9 °C
• Appearance: /
• Density: 1.138 g/cm³
• Vapor Pressure: 0.0297mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), DMSO (Sparingly), Methanol (Sparingly)
• CAS DataBase Reference: 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE(58981-35-4)
• EPA Substance Registry System: 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE(58981-35-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 58981-35-4(Hazardous Substances Data)

Usage

Description

2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is an organic compound with the molecular formula C7H10N2S. It is a derivative of ethanamine, featuring a thiazol ring with a methyl group at the 4-position. 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is known for its potential applications in the pharmaceutical and chemical industries due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is used as a synthetic intermediate for the development of various histamine H2 agonists. These agonists have potential applications in the treatment of various medical conditions, such as peptic ulcers, allergies, and other disorders related to the histamine receptor.
Used in Chemical Research:
2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE is also utilized in the synthesis of novel compounds for chemical research. Its unique structure allows for the exploration of new chemical reactions and the development of innovative molecules with potential applications in various fields, including pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C6H10N2S/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3

Upstream product

• 50382-33-7 (4-methyl-1,3-thiazol-5-yl)acetonitrile 
• 1759-28-0 4-methyl-5-vinylthiazole 
• 533-45-9 chlormethiazole 
• 406727-23-9 (4-methyl-thiazol-5-yl)-acetic acid ethyl ester 
• 136384-13-9 (4-methyl-thiazol-5-yl)-acetic acid amide 
• 137-00-8 5-hydroxyethyl-4-methylthiazole 
• 122-39-4 diphenylamine 
• 153805-36-8 5-(2-azidoethyl)-4-methylthiazole 
• 36956-91-9 4-methyl-5-(β-phthalimidoethyl)thiazole 
• 6508-39-0 3-(4-methyl-thiazol-5-yl)-propionic acid ethyl ester 
• 854473-13-5 3-(4-methyl-thiazol-5-yl)-propionic acid amide 

Downstream Products

• 137-00-8 5-hydroxyethyl-4-methylthiazole 
• 153805-39-1 L-idonamide, 6-cyclohexyl-2,5,6-trideoxy-5-amino-2-(1-methylethyl)-N-<2-methyl-1-<<<2-(4-methyl-5-thiazolyl)ethyl>amino>carbonyl>butyl>-, <3aS-<3aα,4β(1R*,2R*),6aα>>- 
• 153805-38-0 carbamic acid, <1-<2,2-dimethyl-5-<2-cyclohexyl-1-<<<2-methyl-1-<<(2-pyridinylmethyl)amino>carbonyl>butyl>amino>carbonyl>ethyl>-1,3-dioxolan-4-yl>-2-methylpropyl>-, 1,1-dimethylethyl ester, <4R-<4α(R*),5β(S*)>> 

Relevant articles and documents

-

-

Evaluation of a Vitamin-Cloaking Strategy for Oligopeptide Therapeutics: Biotinylated HIV-1 Protease Inhibitors

The outstanding limitations to the oligopeptide as a therapeutic agent are poor oral availability and rapid biliary clearance.To address these concerns a series of eight peptidic HIV-1 protease inhibitors containing the structural segment of the vitamin b