58996-80-8

Basic information

• Product Name: N-p-tolylsulfonyl-2,2'-dipyridylamine
• Synonyms: N-p-tolylsulfonyl-2,2'-dipyridylamine
• CAS NO: 58996-80-8
• Molecular Weight: 325.391
• Mol File: 58996-80-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-p-tolylsulfonyl-2,2'-dipyridylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-p-tolylsulfonyl-2,2'-dipyridylamine(58996-80-8)
• EPA Substance Registry System: N-p-tolylsulfonyl-2,2'-dipyridylamine(58996-80-8)

Safety Data

• Hazardous Substances Data: 58996-80-8(Hazardous Substances Data)

Upstream product

• 694-59-7 pyridine N-oxide 
• 504-29-0 2-aminopyridine 
• 98-59-9 p-toluenesulfonyl chloride 
• 52776-76-8 N-(2-pyridyl)-p-toluenesulfonamide 

Downstream Products

• 1202-34-2 di(pyridin-2-yl)amine 

Relevant articles and documents

A general and efficient 2-amination of pyridines and quinolines

(Chemical Equation Presented) Pyridine N-oxides were converted to 2-aminopyridines in a one-pot fashion using Ts2O-t-BuNH2 followed by in situ deprotection with TFA. The amination proceeded in high yields, excellent 2-/4-selectivity, and with good functional group compatibility. 2-Amino (iso)quinolines were also obtained in the same manner. Combined with the simple oxidation of pyridines to pyridine N-oxides, this method provides a general and efficient way for amination of 2-unsubstituted pyridines.