59057-75-9

Basic information

• Product Name: 7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl acetate
• Synonyms: 7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl acetate
• CAS NO: 59057-75-9
• Molecular Weight: 310.306
• Mol File: 59057-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl acetate(59057-75-9)
• EPA Substance Registry System: 7-methoxy-2-oxo-4-phenyl-2H-chromen-6-yl acetate(59057-75-9)

Safety Data

• Hazardous Substances Data: 59057-75-9(Hazardous Substances Data)

Upstream product

• 482-83-7 6-Hydroxy-7-methoxy-4-phenyl-coumarin 
• 75-36-5 acetyl chloride 
• 52811-37-7 (2,5-dihydroxy-4-methoxyphenyl)phenylmethanone 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Design and synthesis of dalbergin analogues and evaluation of anti-osteoporotic activity

The chemical modifications of the hydroxyl group of dalbergin have been described via the introduction of cyclic amine, ester and amide groups. Among the twenty-three prepared novel analogues of dalbergin, compound 4d (EC50 2.3?μM) showed significantly increased proliferation as assessed by alkaline phosphatase activity and mineralization in calvarial osteoblast cells in vitro. Compound 4d, at a dose of 1.0?mg/kg body weight exhibited the significant osteoprotective effect. It showed a significant increase in osteogenic gene expression RunX2 (～4fold), ALP (～5fold), OCN (～4fold) and COL1 (～4fold) as compared to control group at the same dose in vivo assay.