5909-26-2

Basic information

• Product Name: 2,4-Bis(methylthio)pyrimidine
• Synonyms: 2,4-Bis(methylthio)pyrimidine
• CAS NO: 5909-26-2
• Molecular Formula: C₆H₈N₂S₂
• Molecular Weight: 172.27
• Mol File: 5909-26-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 139-140 °C(Press: 6 Torr)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 1.83±0.20(Predicted)
• CAS DataBase Reference: 2,4-Bis(methylthio)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Bis(methylthio)pyrimidine(5909-26-2)
• EPA Substance Registry System: 2,4-Bis(methylthio)pyrimidine(5909-26-2)

Safety Data

• Hazardous Substances Data: 5909-26-2(Hazardous Substances Data)

Usage

General Description

2,4-Bis(methylthio)pyrimidine is a chemical compound composed of a pyrimidine ring with two methylthio (-SCH3) groups attached at the 2 and 4 positions. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,4-Bis(methylthio)pyrimidine has diverse applications, ranging from its use as a drug intermediate to its role in the development of herbicides and fungicides. Additionally, 2,4-Bis(methylthio)pyrimidine exhibits inhibitory activity against certain enzymes, making it valuable for research in the fields of biochemistry and medicinal chemistry. Its unique chemical structure and versatile biological properties make it a valuable tool for numerous scientific and industrial applications.

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 2001-93-6 2,4-dimercaptopyrimidine 
• 512-56-1 trimethyl phosphite 
• 2001-93-6 2,4-dithiouracil 
• 77-78-1 dimethyl sulfate 
• 3934-20-1 2,6-Dichloropyrimidine 
• 5188-07-8 sodium thiomethoxide 
• 49844-90-8 4-Chloro-2-methylthiopyrimidine 

Downstream Products

• 1080662-19-6 2,4-bis(methylthio-6-(3-trifluoromethylphenyl))pyrimidine 
• 1080662-18-5 4-(2,6-bis(methylthio)pyrimidin-4-yl)-benzoic acid ethyl ester 
• 112380-45-7 2-methylsulfanyl-6-phenyl-5,6-dihydro-3H-pyrimidin-4-one 
• 116137-70-3 4-(2-Methoxy-phenyl)-2,6-bis-methylsulfanyl-pyrimidine 
• 116137-69-0 2,4-Bis-methylsulfanyl-6-phenyl-pyrimidine 
• 6308-41-4 4-methyl-2,6-bis-methylsulfanyl-pyrimidine 

Relevant articles and documents

Regio- and chemoselective magnesiation of protected uracils and thiouracils using TMPMgCl?LiCl and TMP2Mg?2LiCl

Two successive regio- and chemoselective magnesiations using TMPMgCl?LiCl and TMP2Mg?2LiCl enable the full functionalization of protected uracils and thiouracils in good to excellent yields. This journal is

Methylathion of Heterocyclic Compounds Containing NH, SH and/or OH Groups by Means of N,N-Dimethylformamide Dimethyl Acetal

Methylations of heterocyclic systems, such as benzimidazole, naphthimidazole, imidazopyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolopyridazine, which bore SH, NH and/or OH groups, were carried out with dimethylformamide dimethyl acetal to give the corresponding S-, N- and/or O-methyl derivatives in high yields.Selective methylation of some compounds containing both SH and NH groups took place to give first the S-methyl and subsequently the S,N-dimethyl derivatives.No side reactions, such as C-methylation, were observed.